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Local order in protein solutions

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Abstract

Nonlinearity of the dielectric increment of protein solutions as a function of concentration can be explained by the existence of local order. This local order can be expressed in Saupe order parameters. Using a simple mean field theory, it is shown how these order parameters can be obtained. Two cases from the literature are used to illustrate the method.

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References

  1. Spragg, S.P.:The Physical Behavior of macromoleucles with Biological Functions, Wiley, New York, 1980.

    Google Scholar 

  2. DeLaye, M., and Tardieu, A.: Short-range order of crystallin proteins accounts for eye lense transparency,Nature 302 (1983), 415–417.

    Google Scholar 

  3. Hol, W.G.J., van Duynen, P.T. and Berendsen, H.J.C.: The α-helix dipole and the properties of proteins,Nature 273 (1978), 443–446.

    Google Scholar 

  4. Cardinaud, R. and Bernengo, J.C.: Electric birefringence study of skeletal myosin subfragments HMM, LMM, and rod in solution,Biophys. J. 48 (1985), 751–763.

    Google Scholar 

  5. Greulich, K.O., Ausio, J. and Eisenberg, H.: Nucleosome core particle structure and structural changes in solution,J. Mol. Biol. 186 (1985), 167–173.

    Google Scholar 

  6. Moser, P., Squire, P.G. and O'Konski, C.T.: Electric polarization in proteins-dielectric dispersion and Kerr effect studies of isoionic Bovine Serum Albumin,J. Phys. Chem. 70 (1966), 744–756.

    Google Scholar 

  7. Umemura, S., Sakamoto, M., Hayakawa, R. and Wada, Y.: Dielectric relaxation of collagen in aqueous solutions,Biopolymers 18 (1979), 25–34.

    Google Scholar 

  8. Grant, E.H., Sheppard, R.J. and South, G.P.:Dielectric Behavior of Biological Molecules in Solution, Oxford University Press, Oxford, 1978.

    Google Scholar 

  9. Oncley, J.: The investigation of proteins by dielectric measurements,Chem. Rev. 30 (1942), 433–450.

    Google Scholar 

  10. Debye, P.: Der Rotationszustand von Molekülen in Flüssigkeiten,Physik. Z. 36 (1935), 100–101;Polar Molecules, Reinhold, New York, 1929.

    Google Scholar 

  11. Chelkowski, A.:Dielectric Physics, Elsevier, Amsterdam, 1980.

    Google Scholar 

  12. Saupe, A.: Kernresonanzen in kristallinen Flüssigkeiten und in kristallin-flüssigen Lösungen,Z. Naturfors. 19A (1964), 161–171.

    Google Scholar 

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Post, J.F.M. Local order in protein solutions. J Biol Phys 21, 141–144 (1995). https://doi.org/10.1007/BF00705596

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  • DOI: https://doi.org/10.1007/BF00705596

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