Abstract
Recent studies into the mechanisms of uptake of glucose and fructose in S. cerevisiae suggest the existence of at least two transport systems. Based on novel results from our work with glucose, fructose and sucrose, a model of multiple sugars uptake has been developed. This model utilizes a switching concept during the course of batch experiment, the consequences of which are discussed.
Similar content being viewed by others
References
Steveninck, J. van: Transport associated phosphorylation of 2-deoxy-D-glucose in yeast. Biochim. Biophys. Acta. 163 (1938) 386–391
Meredith, S. A.; Romano, A. H.: Uptake and phosphorylation of 2-deoxy-D-glucose by wild type and respiration deficient baker's yeast. Biochim. Biophys. Acta. 497 (1977) 745–759.
Cirrilo, V. P.: The mechanism of sugar transport into the yeast cell. NY Academy Sci. Trans. Series B 23 (1961) 725–734
Romano, A. H.: Facilitated diffusion of 6-deoxy-D-glucose in baker's yeast: Evidence against phosphorylation associated transport of glucose. J. Bacteriol. 152 (3) (1982) 1295–1297
Steveninck, J. van; Rothstein, A.: Sugar transport and metal binding in yeast. J. Gen. Physiol. 49 (1965) 235–246
Kotyk, A.: Properties of the sugar carrier in baker's yeast II. Specifity of transport. Folia Microbiol., 12 (1967) 121–131
Soumalainen, H.; Oura, E.: Yeast nutrition and solute uptake. In: A. H. Rose and J. S. Harrison (Eds.): The yeasts, vol 2, pp 3–74, London: Academic Press 1971
Belaich, J.-P.; Senez, J. C.; Murgier, M.: Microcalorimetric study of glucose permeation in microbial cells. J. Bacteriol. 95 (1968) 1750–1757
Bisson, L. F.; Fraenkel, D. G.: Involvement of kinases in glucose and fructose uptake by S. cerevisiae. Proc. Natl. Acad. Sci. USA. 80 (1983) 1730–1734
Bisson, L. F.; Fraenkel, D. G.: Transport of 6-deoxy-D-glucose in S. cerevisiae. J. Bacteriol. 155 (1983) 995–1000
Bisson, L. F.; Neigeborn, L.; Carlson, M.; Fraenkel, D. G.: The SNF3 gene is required for high-affinity glucose transport by S. cerevisiae. J. Bacteriol. 169 (1987) 1656–1662
Orlowski, J. H.; Barford, J. P.: The mechanism of uptake of multiple sugars by S. cerevisiae in batch culture under fully aerated conditions. Appl. Micro. Biotechnol. 25 (1987) 459–463
Panchal, C. J.; Stewart, G. G.: Utilisation of wort carbohydrates. The Brewers Digest, June (1979) 36–46
Panchal, C. J.; Stewart, G. G.: The influence of media conditions on the utilisation of monosaccharides by a strain of Saccharomyces uvarum (carlsbergensis). Inst. Brew. J. 88 (1982) 86–89
Orlowski, J. H.: The kinetics of uptake and metabolism of glucose, fructose and Sucrose by S. cerevisiae. PhD Thesis, University of Sydney (1987)
Barford, J. P.; Hall, R. J.: A mathematical model for the aerobic growth of S. cerevisiae with a saturated respiratory capacity. Biotechnol. Bioeng. 23 (1981) 1735–1762
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Barford, J.P., Phillips, P.J. & Orlowski, J.H. A new model of uptake of multiple sugars by S. cerevisiae. Bioprocess Engineering 7, 297–302 (1992). https://doi.org/10.1007/BF00705158
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00705158