Preparation ofN-chloroacetyl-N′-arylsulfonylureas and the crystal structure ofN-chloroacetyl-N′-(4-methylphenylsulfonyl)urea
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Novel arylsulfonylureas were prepared by the reaction of chloroacetyl isocyanate with arylsulfamides. The structures of the compounds synthesized were determined by IR and1H NMR spectra. An X-ray structural analysis ofN-chloroacetyl-N′-(4-methylphenylsulfonyl)urea was carried out. It was found that the molecule has theanti-syn conformation stabilized by an intramolecular H-bond. In the crystal, the molecules are combined into centrosymmetrical dimers by intermolecular hydrogen bonds. The compounds considered exhibit moderate fungicide activity.
Key wordsN-chloroacetyl-N′-arylsulfonylureas X-ray diffraction analysis hydrogen bonds chloroacetyl isocyanate arylsulfamides biological activity
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