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Humangenetik

, Volume 12, Issue 3, pp 257–260 | Cite as

Fluorochromierung menschlicher Chromosomen mit Atebrin-Essigsäure

  • A. Kim
  • L. Bier
  • F. Majewski
  • R. A. Pfeiffer
Kurze Originalmitteilungen

Zusammenfassung

Es wird eine Technik zur Fluorochromierung menschlicher Chromosomen angegeben, die ein differenziertes Fluorescenzmuster hervortreten läßt.

Staining of human chromosomes with acetic acid-quinacrine

Summary

A technic for staining human chromosomes is described which shows differentiated fluorescence.

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Literatur

  1. Caspersson, T., Farber, S., Foley, G. E., Kudynowski, I., Modest, E. J., Simonsson, E., Wagh, U., Zech, L.: Chemical differentiation along metaphase chromosomes. Exp. Cell Res.49, 219 (1968).Google Scholar
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  7. O'Brien, R. L., Olenick, J. G., Hahn, F. E.: Reaction of Quinine, Chloroquine and Quinacrine with DNA and their effects on the DNA and RNA polymerase reactions. Proc. nat. Acad. Sci. (Wash.)55, 1511 (1966).Google Scholar
  8. Pearson, P. L., Bobrow, M.: Definitive evidence for the short arm of the Y chromosome associating with the X chromosome during meiosis in the human male. Nature (Lond.)226, 959 (1970).Google Scholar
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  11. Zech, L.: Investigation of metaphase chromosomes with DNA-binding fluorochromes. Exp. Cell Res.58, 463 (1969).Google Scholar

Copyright information

© Springer-Verlag 1971

Authors and Affiliations

  • A. Kim
    • 1
  • L. Bier
    • 1
  • F. Majewski
    • 1
  • R. A. Pfeiffer
    • 1
  1. 1.Abteilung für Klinische Genetik und Cytogenetik im Institut für Humangenetik der Westfälischen Wilhelms-Universität MünsterMunsterDeutschland

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