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A method for predicting the volume of an ileo-anal pouch

  • J. G. Williams
  • J. A. Heine
  • D. L. Stoller
  • D. A. Rothenberger
Original Articles

Abstract

Functional outcome following restorative proctocolectomy depends, in part, on the volume of the pouch. This study investigates the relationship between the length of ileum and volume of saline required to distend the ileum to a set pressure, and the possibility of predicting the volume of an ileoanal pouch using these measurements. Measurements were made on the ileum of 8 mongrel dogs. There was a linear relationship between the length of ileum and volume of saline infused to produce an intraluminal pressure of 20 mmHg (r=0.94-0.99). However, the capacity of ileum varied widely from animal to animal (100 cc of saline filled 15.5 cm to 43 cm of ileum). Twenty-four pouches (15J, 9S) were constructed from segments of ileum of known capacity. The capacity of a J pouch was 1.7±0.11 times greater than the capacity of the original length of bowel and an S pouch had a capacity 2.14±0.25 times greater. These changes in capacity are similar to a theoretical calculation of change in volume of ileum after pouch construction. This technique is a simple, quick method of predicting the volume of an ileo-anal pouch which will be useful in a clinical trial to compare function of pouches of different volumes.

Keywords

Public Health Clinical Trial Internal Medicine Linear Relationship Functional Outcome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Résumé

La résultat fonctionnel des proctocolectomies avec réservoir iléo-anal résulte en partie du volume de la poche. Ce travail étudie la relation entre la longueur de l'iléon et le volume de sérum nécessaire pour distendre l'iléon jusqu'à une pression donnée ainsi que la possibilité de prédire le volume d'une poche iléoanale sur la base de ces mesures. Les mensurations ont été obtenues sur l'iléon de 8 chiens. Une relation linéaire s'établit entre la longueur de l'iléon et le volume de sérum à infuser pour obtenir une pression intraluminale de 20 mmHg (r=0,94-0,99). La capacité de l'iléon varie toutefois grandement d'un animal à l'autre (100 ml de soluté physiologique pour remplir de 15,5 cm à 43 cm d'iléon). Vingt quatre poches (15J, 9S) ont été confectionnées à partir de segments d'iléon de capacité connue. La capacité d'une poche en J est 1,71±0,11 fois supérieure à la capacité de la longueur originale de l'intestin et une poche en S a une capacité de 2,14±0,25 fois supéricure à la capacité originale de l'intestin. Ces changements dans la capacité sont similaires à ceux que l'on peut calculer de manière théorique dans le volume de l'iléon après confection d'une poche. Cette technique est simple et permet un calcul rapide du volume d'une poche iléoanale; elle sera particulièrement utile dans des études cliniques pour comparer le fonctionnement de poches de différents volumes.

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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • J. G. Williams
    • 1
  • J. A. Heine
    • 1
  • D. L. Stoller
    • 1
  • D. A. Rothenberger
    • 1
  1. 1.Division of Colon and Rectal SurgeryUniversity of MinnesotaMinneapolisUSA

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