Russian Chemical Bulletin

, Volume 43, Issue 1, pp 110–113 | Cite as

Synthesis of 3-thienyl substituted 2-pyrazolines by 1,3-dipolar cycloaddition

  • M. M. Krayushkin
  • M. A. Kalik
  • S. A. Voznesensky
Organic Chemistry
  • 29 Downloads

Abstract

1,3,5-Trisubstituted 3-thienylpyrazolines have been prepared in high yields by the reaction of substituted,N-(P;-nitrophenyl)-3-thiophenecarbohydrazonoyl chlorides with Et3N in CH2Cl2 in the presence of an excess of a monosubstituted olefin. The reaction probably occurs as 1,3-dipolar cycloaddition of the corresponding 3-thiophenecarbonitrile imines formedin situ at the double bond of the olefin.

Key words

1,3-dipolar cycloaddition hydrazonoyl chlorides 3-thienylpyrazolines 3-thienylpyrazoles 

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Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • M. M. Krayushkin
    • 1
  • M. A. Kalik
    • 1
  • S. A. Voznesensky
    • 1
  1. 1.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussian Federation

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