Summary
Ninety-six magnetic resonance imaging (MRI) studies demonstrating solitary brain stem lesions were reviewed in order to establish distinguishing features between tumours and other lesions. Histological confirmation of the radiological diagnoses was obtained in 33% of patients. The morphology of the lesion rather than its signal characteristics was the most useful feature in differential diagnosis, except after haemorrhage. However, areas of abnormal T2 recovery time were significantly more extensive than areas of abnormal T1 recovery time in tumours at presentation. In other lesions and in tumours following radiotherapy induced regression, the extent of abnormal T1 and T2 signal was the same. Possible reasons for this observation are discussed. The accuracy of computed tomography (CT) and MRI were similar for lesions causing brain stem expansion but for small lesions MRI was more sensitive and provided better topographical information.
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References
Bradac GB, Schorner W, Bender A, Felix R (1985) MRI (NMR) in the diagnosis of brain stem tumours. Neuroradiology 27: 208–213
Hueftle MG, Han JS, Kaufman B, Benson JE (1985) MR imaging of brain stem gliomas. J Comput Assist Tomogr 9: 263–267
Peterman SB, Steiner RE, Bydder GM, Thomas DJ, Tobias JS, Young IR (1985) Nuclear magnetic resonance imaging (NMR), (MRI), of brain stem tumours, Neuroradiology 27: 202–207
Zimmerman RA, Bilaniuk LT, Packer R, Sutton L, Samuel L, Johnson MH, Grossman RI, Goldberg HI (1985) Resistive NMR of brain stem gliomas. Neuroradiology 27: 21–25
Lee BC, Kneeland JB, Deck MDF, Cahill PT (1984) Posterior fossa lesions: magnetic resonance imaging. Radiology 153: 137–143
Bydder GM, Steiner RE, Thomas DJ, Marshall J, Gilderdale DJ, Young IR (1983) Nuclear magnetic resonance of the posterior fossa: 50 cases. Clin Radiol 34: 173–188
MacDonald HL, Bell BA, Smith MA, Kean DM, Tocher JL, Douglas RHB, Miller JD, Best JJK (1986) Correlation of human NMR T1 values measured in vivo and brain water content. Br J Radiol 59: 355–357
Naruse S, Horikawa Y, Tanaka C, Hirakawa K, Nishikawa H, Yoshizaki K (1982) Proton nuclear magnetic resonance studies on brain edema. J Neurosurg 56: 747–752
Stroink AR, Hoffman HJ, Hendrick EB, Humphreys RP (1986) Diagnosis and management of paediatric brain-stem gliomas. J Neurosurg 65: 745–750
Cohen ME, Duffner PK, Heffner RR, Lacey DJ, Brecker M (1986) Prognostic factors in brain stem gliomas. Neurology 36: 602–605
Albright AL, Guthkelch AN, Packer RJ, Price RA, Rourke LB (1986) Prognostic factors in pediatric brain stem gliomas. J Neurosurg 65: 751–755
Gomori JM, Grossman RI, Goldberg HI, Zimmerman RA, Bilaniuk LT (1985) Intracranial hematomas: imaging by highfield MR. Radiology 157: 87–93
Zimmerman RD, Heier LA, Snow RB, Kelly AB, Deck MDF (1988) Acute intracranial hemorrhage: intensity changes on sequential MR scans at 0.5 T. AJNR 9: 47–57
Dooms GC, Hecht S, Brand-Zawadzki M, Berthiaume Y, Norman D, Newton TH (1986) Brain radiation lesions: MR imaging. Radiology 158: 149–155
Packer RJ, Zimmerman RA, Luerssen TG, Sutton LN, Bilaniuk LT, Bruce DA, Schut L (1985) Brainstem gliomas of childhood: Magnetic resonance imaging. Neurology 35: 397–401
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Byrne, J.V., Kendall, B.E., Kingsley, D.P.E. et al. Lesions of the brain stem: assessment by magnetic resonance imaging. Neuroradiology 31, 129–133 (1989). https://doi.org/10.1007/BF00698839
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DOI: https://doi.org/10.1007/BF00698839