Acta Neuropathologica

, Volume 66, Issue 1, pp 83–86 | Cite as

Polyglucosan bodies in the sural nerve of a diabetic patient with polyneruopathy

  • G. L. Mancardl
  • A. Schenone
  • M. Tabaton
  • T. Tassinari
  • P. Mainardi
Short Original Communications


In the sural nerve of a 62-year-old woman with impaired glucose tolerance test and polyneuropathy, many intra-axonal polyglucosan bodies were observed. Polyglucosan bodies have been described in spontaneously or alloxan-diabetic rats, but are not usually observed in human diabetic neuropathy. Since intra-axonal polyglucosan bodies can occur in the sural nerve in various diseases and in aging, they are considered as non-specific changes. Their presence is probably related to a primary axonal neuropathy.

Key words

Axonal neuropathy Diabetic neuropathy Polyglucosan bodies 


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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • G. L. Mancardl
    • 1
  • A. Schenone
    • 1
  • M. Tabaton
    • 1
  • T. Tassinari
    • 1
  • P. Mainardi
    • 1
  1. 1.Clinica NeurologicaUniversità di GenovaGenovaItaly

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