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Synthesis of α-(4-hydroxyphenyl)-β,β,β-trifluoro-α-alanine derivatives

  • Organic Chemistry
  • Published:
Russian Chemical Bulletin Aims and scope

Abstract

2,6-Dimethyl- and 2,6-dimethoxy-α-methoxycarbonyl-α-trifluoromethyl-p-methylenequinones have been synthesized. These compounds easily react with ammonia, morpholine, andp-toluidine to afford the corresponding α-(4-hydroxyphenyl)-β,β,β-trifluoro-α-alanine derivatives.

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Authors and Affiliations

  1. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 ul. Vavilova, 117813, Moscow, Russian Federation

    V. I. Dyachenko, A. F. Kolomiets & A. V. Fokin

Authors
  1. V. I. Dyachenko
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  2. A. F. Kolomiets
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  3. A. V. Fokin
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Additional information

Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 9, pp. 1631–1633, September, 1994.

This work was financially supported by the Russian Foundation for Basic Research (Project No. 93-0322696).

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Dyachenko, V.I., Kolomiets, A.F. & Fokin, A.V. Synthesis of α-(4-hydroxyphenyl)-β,β,β-trifluoro-α-alanine derivatives. Russ Chem Bull 43, 1543–1545 (1994). https://doi.org/10.1007/BF00697145

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  • DOI: https://doi.org/10.1007/BF00697145

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