Russian Chemical Bulletin

, Volume 42, Issue 2, pp 328–333 | Cite as

Synthesis and structure of diastereomeric trans-3,4-diamino-2,2,6,6-tetramethylpiperidine1-oxyl derivatives

  • V. D. Sen'
  • V. V. Tkachev
  • L. O. Atovmyan
Organic Chemistry

Abstract

The reaction of 3,4-diamino-2,2,6,6-tetramethylpiperidine-1-oxyl with (1S)-(+)-camphor-10-sulfonyl chloride gives a mixture of diastereomeric 4-monosulfonylamino derivatives. The products of their acylation have been obtained. The 3,4-bis-[(1S)-camphor-10-sulfonylamino] derivative was synthesized and resolved to individual diastereomers. For one of them thetrans relationship of the 3- and 4-substituents and the absolute (3S,4R)-configuration were established by X-ray structural analysis.

Key words

trans-3.4-diamino-2,2,6,6-tetramethylpiperidine-1-oxyl diastereomeric derivatives, resolution structure absolute configuration 

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Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • V. D. Sen'
    • 1
  • V. V. Tkachev
    • 1
  • L. O. Atovmyan
    • 1
  1. 1.Institute of Chemical Physics in ChernogolovkaRussian Academy of SciencesChernogolovkaRussian Federation

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