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Thessaly variant of Glucose-6-phosphate Dehydrogenase

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Summary

A new variant of the erythrocytic enzyme Glucose-6-phosphate Dehydrogenase was detected in two unrelated Greek individuals. The variant was designated G6PD Thessaly. It is characterized by normal levels of G6PD activity in the red cells and electrophoretic migration slower than G6PD B on phosphate and T.E.B. buffers while faster than G6PD B on Tris-HCl buffer. In addition, the Thessaly variant has distinctly decreased affinity for NADP.

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Authors and Affiliations

  1. Department of Medicine, Division of Medical Genetics, University of Washington, 98105, Seattle, Washington, USA

    G. Stamatoyannopoulos, V. Voigtländer & A. Akrivakis

Authors
  1. G. Stamatoyannopoulos
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  2. V. Voigtländer
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  3. A. Akrivakis
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Additional information

This study was supported by National Institutes of Health Grant GM 15253.

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Stamatoyannopoulos, G., Voigtländer, V. & Akrivakis, A. Thessaly variant of Glucose-6-phosphate Dehydrogenase. Humangenetik 9, 23–25 (1970). https://doi.org/10.1007/BF00696009

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  • DOI: https://doi.org/10.1007/BF00696009

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