Endosulfan poisoning and chronic brain syndrome
- 50 Downloads
The author describes a case of acute poisoning by endosulfan (a chlorinated hydrocarbon insecticide) in an industrial worker, with residual psychiatric syndrome. The acute phase was manifested by repeated convulsions and impaired consciousness. After recovery the patient became disoriented and agitated. The residual phase, 2 years after initial hospitalization, was manifested by cognitive and emotional deterioration, severe impairment of memory and inability to perform any but the simplest tasks. Psychological tests revealed gross impairment of visual-motor coordination. The differential diagnosis of chronic brain syndrome requires accurate history and milder cases of endosulfan poisoning may easily be overlooked or misdiagnosed.
Key wordsChronic brain damage Organochlorine insecticides Endosulfan (thiodan) Bender-Gestalt test
Unable to display preview. Download preview PDF.
- Gupta, P. K.: Endosulfan-induced neurotoxicity in rats and mice. Bull. Environ. Contam. Toxicol.15, 708–713 (1976)Google Scholar
- Quaraishi, M. S.: Biochemical insect control. New York: Wiley 1977Google Scholar
- Stevens, H.: Neurotoxicity of some common halogenated hydrocarbons. In: Laboratory diagnosis of diseases caused by toxic agents (F. W. Sunderman, and F. W. Sunderman, Jr., eds.), pp. 196–198. St. Louis, MO.: Warren H. Green 1970Google Scholar
- Terziev, G., Dimitrova, N., Rusev, P.: Forensic medical and forensic chemical study of acute lethal poisoning with thiodan. Folia Med. (Plovdiv)15, 325–329 (1974)Google Scholar
- Thompson, G. E.: Poisoning of cattle following accidental spraying with thiodan. J. S. Afr. Vet. Assoc.37, 81–83 (1966)Google Scholar