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Is the excretion of sebum regulated?

Archives of Dermatological Research volume 266, pages 127–133 (1979)Cite this article

Summary

The kinetics of sebum excretion on the forehead of volunteers were measured over a period of at least 7 h. The transmission data obtained by the ground glass method were transformed into weight (sebum/cm2). The excretion time function can be described by the equation:

$$w = A \cdot (1 - B \cdot {\text{e}}^{ - C \cdot t} )$$

This nonlinear function is typical for modes of excretion in the biological field. Regulation of sebum excretion is probable. Objections against such regulation by feedback were discussed.

Zusammenfassung

Die Kinetik der Talgausscheidung wurde auf der Stirn von freiwilligen Versuchspersonen über einen Zeitraum von mindestens 7h gemessen. Die mit der Rauhglas-Methode erhaltenen Transmissionswerte wurden in μg Talg pro cm2 umgerechnet. Die Ausscheidungsfunktion kann durch folgende Gleichung beschrieben werden:

$$w = A \cdot (1 - B \cdot {\text{e}}^{ - C \cdot t} )$$

Diese nichtlineare Funktion ist typisch für Ausscheidungsvorgänge im biologischen Bereich. Eine Regulation der Talgausscheidung ist wahrscheinlich. Einwände gegen eine Regulation der Talgausscheidung (Feedback Theorie) werden diskutiert.

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References

  1. Schur, H., Goldfarb, L.: Zur Physiologie und Pathologie der Talgsekretion. Wien. Klin. Wochenschr.40, 1255 (1927)

    Google Scholar 

  2. Emanuel, S.: Mechanism of the sebum secretion. Acta Derm. Venerol.19, 1 (1938)

    Google Scholar 

  3. Butcher, E. O., Coonin, A.: The physical properties of human sebum. J. Invest. Dermatol.12, 249 (1949)

    Google Scholar 

  4. Kligman, A. M., Shelley, W. B.: An investigation of the biology of the human sebaceous gland. J. Invest. Dermatol.30, 99–124 (1958)

    Google Scholar 

  5. Eberhardt, H.: The regulation of sebum excretion in man. Arch. Dermatol. Forsch.251, 155–164 (1974)

    Google Scholar 

  6. Strauss, J.S., Pochi, P. E., Downing, D. T.: The sebaceous glands: Twenty-five years of progress. J. Invest. Dermatol.67, 90–95 (1976)

    Google Scholar 

  7. Schaefer, H., Kuhn-Bussius, H.: Methodik zur quantitativen Bestimmung der menschlichen Talgsekretion. Arch. Klin. Exp. Dermatol.238, 429–435 (1970)

    Google Scholar 

  8. Bliss, C. J.: Statistics in Biology, Vol. 2, p. 119. New York: McGraw-Hill Book Comp. 1970

    Google Scholar 

  9. Artuc, M.: Diplomarbeit 1976, Techn. Universität Berlin, Max-Volmar-Institut f. Physikal. Chem. Molekularbiol.

  10. Burton, J. L.: Factors affecting the rate of sebum excretion in man. J. Soc. Cosm. Chem.23, 241–258 (1972)

    Google Scholar 

  11. Landsberg, I. I.: Some useful equations for biological studies. Expl. Agric.13, 273–286 (1977)

    Google Scholar 

  12. Dixon, W. I.: BMD, Biomedical Computer Programs, 3rd ed. Berkeley: University of California Press 1976

    Google Scholar 

Download references

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Authors and Affiliations

  1. Forschungslaboratorien der Dr. Karl Thomae GmbH, D-7950, Biberach/Riß, Federal Republic of Germany

    H. Eberhardt & G. Trieb

Authors
  1. H. Eberhardt
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  2. G. Trieb
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Eberhardt, H., Trieb, G. Is the excretion of sebum regulated?. Arch Dermatol Res 266, 127–133 (1979). https://doi.org/10.1007/BF00694622

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  • DOI: https://doi.org/10.1007/BF00694622

Key words

  • Sebum excretion
  • Kinetics
  • Nonlinear function

Schlüsselwörter

  • Talgausscheidung
  • Kinetik
  • nichtlineare Funktion