Journal of comparative physiology

, Volume 84, Issue 3, pp 267–279 | Cite as

Single neurone responses to tactile stimulation of the heart in the snail,Helix pomatia L.

  • Katalin S.-Rózsa
  • J. Salánki


The electrical activity of the heart nerve and of single neurons in the suboesophageal ganglia were recorded during tactile stimulation of the heart. 15 neurons were identified which responded to heart stimulation by inhibiting or accelerating activity. Cells influenced by heart afferents are scattered in the visceral and in the right and left parietal ganglia.

In most of the cases both decrease and increase of cell activity are caused by synaptic potentials, in some cases, however, the neuron is assumed to have a sensory character.

The activity of three neurons influenced by heart stimulation was conducted into the heart nerve. These cells are central neurons of a heart-CNS-heart reflex.

Some of the neurons located in the right parietal and visceral ganglia have no connection with the mechanoreceptors of the heart. Since their spikes propagate into the heart nerve, they probably take part in the extracardial regulation of heart activity.

One of the neurons located in the visceral ganglion (cell V12) sends its axon into the heart nerve. The response of this neuron to heart stimulation was an increase in activity and an inhibition of the heart rate. This is an inhibitory neuron of the extracardial heart regulatory system.


Heart Rate Cell Activity Regulatory System Electrical Activity Single Neuron 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Carlson, A. J.: Comparative physiology of the invertebrate heart. III. Physiology of the cardiac nerves in molluscs. Amer. J. Physiol.14, 14–53 (1905).Google Scholar
  2. Gubicza, A., S.-Rózsa, K.: Identification of central neurons innervating the heart of Lymnaea stagnalis L. (Gastropoda). Ann. Biol. Tihany36, 3–10 (1969).Google Scholar
  3. Hughes, G. M., Tauc, L.: Aspects of the organization of central nervous pathways in Aplysia depilans. J. exp. Biol.39, 45–69 (1962).Google Scholar
  4. Kiss, T., Elekes, K.: Myo-neural junctions in the ventricle of the snailHelix pomatia L. Acta biol. Acad. Sci. hung.23, 207–211 (1972).Google Scholar
  5. Koshtoyants, H. S., Smirnova, N. A., Popkova, R. S.: The cerebral and abdominal ganglia and the regulation of cardiac activity inHelix pomatia. Sechenov physiol. J. U.S.S.R.45, 1236–1241 (1956).Google Scholar
  6. Krijgsman, B. J., Divaris, G. A.: Contractile and pacemaker mechanisms of the heart of Molluscs. Biol. Rev.30, 1–39 (1955).Google Scholar
  7. Kupferman, I., Kandel, E. R.: Neuronal controls of a behavioural response mediated by the abdominal ganglion of Aplysia. Science164, 847–850 (1969).Google Scholar
  8. Kupferman, I., Pinsker, H., Castellucci, V., Kandel, E. R.: Central and peripheral control of gill movements in Aplysia. Science174, 1252–1256 (1971).Google Scholar
  9. Kuwasawa, K., Hill, R. B.: Regulation of ventricular rhythmicity in the hearts of prosobranch Gastropods, (in press). In: Neurobiology of invertebrates. Mechanisms of rhythm regulation, ed. J. Salánki. Budapest: Akadémiai Kiadó 1973.Google Scholar
  10. McKay, A. R., Gelperin, A.: Pharmacology and reflex responsiveness of the heart in the giant garden slug,Limax maximus. Comp. Biochem. Physiol.43A, 877–896 (1972).Google Scholar
  11. Mellon, F. de: Electrophysiology of touch sensitive neurons in a Mollusc. J. comp. Physiol.79, 63–78 (1972).Google Scholar
  12. Meng, K.: 5-Hydroxytryptamine und Acetylcholine als Wirkungsantagonisten beim Helix-Herzen. Naturwissenschaften19, 470–481 (1958).Google Scholar
  13. Peretz, B.: Central neuron inhibition of periodic gill movements. Science166, 1167–1172 (1969).Google Scholar
  14. Ripplinger, J.: Contribution a l'étude de la physiologie du coeur et son innervation extrinséque chez l'escargot (Helix pomatia). Ann. Sci. l'Université de Besancon, 2me Série, Zool. Physiol.8, 3–179 (1957).Google Scholar
  15. Sakharov, D. A., Salánki, J.: Physiological and pharmacological identification of neurons in the central nervous system ofHelix pomatia L. Acta physiol. Acad. Sci. hung.35, 19–30 (1969).Google Scholar
  16. Salánki, J., Vadász, I., Véró, M.: Physiological and morphological characteristics of Br-type neuron in the central nervous system of theHelix pomatia L. Acta physiol. Acad. Sci. hung. in press.Google Scholar
  17. S.-Rózsa, K.: Characterization of the feed-back system in the heart ofHelix pomatia L. Ann. Biol. Tihany39, 29–38 (1972).Google Scholar
  18. S.-Rózsa, K., Graul, S.: Is serotonin responsible for the stimulative effect of the extracardiac nerve inHelix pomatia? Ann. Biol. Tihany31, 85–96 (1964).Google Scholar
  19. S.-Rózsa, K., Perényi, L.: Chemical identification of the excitatory substance released in Helix heart during stimulation of the extracardial nerve. Comp. Biochem. Physiol.19, 105–113 (1966).Google Scholar
  20. S.-Rózsa, K., Zs.-Nagy, I.: Physiological and histochemical evidence for neuroendocrine regulation of heart activity in the snail Lymnaea stagnalis L. Comp. Biochem. Physiol.23, 373–382 (1967).Google Scholar
  21. Tiel, N. van: Untersuchungen über die nervöse Regulierung des Gastropoden-Herzens. Arch. néerl. Physiol.26, 269–296 (1942).Google Scholar
  22. Véró, M.: Negative capacitance amplifier for microelectrode investigations. Ann. Biol. Tihany38, 107–115 (1971).Google Scholar
  23. Vlieger, T. A. de: Postganglionic responses upon tactile stimulation inLymnaea stagnalis (L.). Neth. J. Zool.20, 492–495 (1970).Google Scholar
  24. Weevers, R. G.: A preparation ofAplysia fascinata for intrasomatic recording and stimulation of single neurons during locomotor movements. J. exp. Biol.54, 659–676 (1971).Google Scholar
  25. Welsh, J.: Neurohormones of Mollusca. Amer. Zoologist1, 267–272 (1961).Google Scholar
  26. Wilgenburg, H.: An electrophysiological analysis of neurons in the visceral and parietal ganglia ofHelix pomatia L. Nooys Drukkerij-Purmerend 1970.Google Scholar
  27. Willows, A. O. D., Hoyle, G.: Correlation of behaviour with the activity of single identifiable neurons in the brain of Tritonia, p. 443–461. In: Neurobiology of invertebrates, ed. J. Salánki. New York: Plenum Press and Akadémiai Kiadó, Budapest: 1968.Google Scholar
  28. Zubkov, A. A.: Materialien zur vergleichenden Physiologie des Herzens. II. Die Rolle des zentralen Nervensystems in der Herztätigkeit derHelix pomatia. Fiziol. Z.17, 293–313 (1935).Google Scholar

Copyright information

© Springer-Verlag 1973

Authors and Affiliations

  • Katalin S.-Rózsa
    • 1
  • J. Salánki
    • 1
  1. 1.Biological Research Institute of the Hungarian Academy of SciencesTihany

Personalised recommendations