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Nuclear inclusion in oculopharyngeal dystrophy

Acta Neuropathologica volume 49, pages 85–87 (1980)Cite this article

Summary

The ultrastructural examination of skeletal muscle biopsies of three typical cases of autosomal dominant inherited oculopharyngeal muscular dystrophy showed collections of tubular filaments (8.5 nm in diameter) within muscle fibre nuclei. These filaments appear to be a characteristic morphological feature of oculopharyngeal dystrophy.

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Authors and Affiliations

  1. Groupe de Recherches de Biologie et Pathologie Neuromusculaires, INSERM U. 153, 17 rue du Fer à Moulin, F-75005, Paris, France

    F. M. S. Tomé (Chargé de Recherches (INSERM) & M. Fardeau (Directeur de Recherches (CNRS), E. R. 107)

Authors
  1. F. M. S. Tomé
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  2. M. Fardeau
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Tomé, F.M.S., Fardeau, M. Nuclear inclusion in oculopharyngeal dystrophy. Acta Neuropathol 49, 85–87 (1980). https://doi.org/10.1007/BF00692226

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  • DOI: https://doi.org/10.1007/BF00692226

Key words

  • Oculopharyngeal muscular dystrophy
  • Muscle biopsy
  • Nuclear inclusions
  • Electron microscopy