Acta Neuropathologica

, Volume 55, Issue 3, pp 243–246 | Cite as

Pineoblastoma with ganglionic and glial differentiation

Report of two cases
  • R. A. Sobel
  • J. E. Trice
  • S. L. Nielsen
  • W. G. Ellis
Short Original Communication


Two cases of pineoblastoma in infants are reported. Both cases exhibited ganglionic and astrocytic differentiation, and one case also showed retinoblastomatous features. Divergent differentiation has been frequently reported in pineocytomas, but ganglionic and glial features in the highly malignant primitive pineoblastoma are unusual. These cases extend the concept of pineoblastoma and further confirm the differentiating potential of primary pineal parenchymal neoplasms.

Key words

Pineal Pinealoma 


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Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • R. A. Sobel
    • 1
  • J. E. Trice
    • 2
  • S. L. Nielsen
    • 3
  • W. G. Ellis
    • 3
  1. 1.Dept. of Pathology (Neuropathology)Stanford University School of MedicineStanfordUSA
  2. 2.Dept. of Pathology, Rhode Island HospitalBrown University School of MedicineProvidenceUSA
  3. 3.Dept. of PathologyUniversity of California Davis School of MedicineSacramentoUSA

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