Acta Neuropathologica

, Volume 38, Issue 1, pp 11–19 | Cite as

Membrane structures of human oligodendroglioma

  • Eiichi Tani
  • Yukio Maeda
  • Shigeatsu Natsume
  • Yuko Ito
Original Investigations


Plasma membrane particles of four human oligodendrogliomas were distributed at random, and their average number per μm2 plasma membrane was 1090±233 on face A and 230±46 on face B. Gap junction was occasionally visible, usually small in size and composed of a polygonal aggregate of several subunits; isodiametric particles, about 70–80 Å in diameter, on face A and pits, about 30–40 Å in diameter, on face B. Tight junction in two oligodendrogliomas was characterized by a meshwork of circular or ramifying crests on face A and complementary furrows on face B. It was often continuous in distribution, consisting of 5 or more strands. In addition, many particulate structures, occasionally fibrillar ones, of ridge materials were often visible in the bottoms of furrows, and a few particles were scatteredly found on the tops of crests. The ridge materials,if added together on crests and furrows, were linearly continuous in some case and discontinuous in other.

Key words

Oligodendroglioma Membrane particles Gap junction Tight junction Ridge materials 


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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • Eiichi Tani
    • 1
  • Yukio Maeda
    • 1
  • Shigeatsu Natsume
    • 1
  • Yuko Ito
    • 1
  1. 1.Department of NeurosurgeryHyogo College of MedicineHyogoJapan

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