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Acta Neuropathologica

, Volume 4, Issue 6, pp 669–682 | Cite as

Neuroreticuloses

  • St. DrĂgĂnescu
  • O. Vuia
Original Investigations

Summary

The authors report on 5 cases, the histopathologic study of which made evident a cellular proliferative process starting from the Virchow-Robin-spaces with predominant lesions around the ventricles. A closer examination showed foci of productive granulomatous inflammatory type and, in three of the cases, also proliferations of a definite tumorous character. The main cell in both types of lesions (granulomatous and blastomatous) was the reticular histio-monocyte.

Both the general pathologic and the cytologic aspect classify these cases in the group of primary cerebral reticuloendotheliosis (Wilke), which in their turn may have a purely inflammatory aspect (granulomatous reticulohistiocytic encephalitis,Cervos-Navarro), or a tumorous proliferative aspect (true neuroreticulosis).

Keywords

Public Health Histopathologic Study Main Cell Proliferative Process Inflammatory Type 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Bericht über 5 Fälle, deren histopathologische Untersuchungen einen zelligen Proliferationsprozeß aufdeckte, der aus den Virchowschen Räumen seinen Ausgang nimmt und vorwiegend um die Ventrikel lokalisiert ist. Die Feinuntersuchung erwies in 3 dieser Fälle Herde vom Typ einer produktiven granulomatösen Entzündung sowie Proliferationen von ausgesprochenem Tumorcharakter. Die vorherrschende Zelle in beiden Läsionstypen (granulomatöse und blastomatöse) war der retikuläre Histiomonocyt. Sowohl nach dem allgemein pathologischen wie nach dem cytologischen Aspekt sind diese Fälle als primäre cerebrale Reticuloendotheliose (Wilke) zu klassifizieren, die ihrerseits einen rein entzündlichen Aspekt (granulomatöse reticulohistiocytäre EncephalitisCervos-Navarro) oder einen proliferativen Tumoraspekt (echte Neuroreticulose) haben kann.

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Copyright information

© Springer-Verlag 1965

Authors and Affiliations

  • St. DrĂgĂnescu
    • 1
  • O. Vuia
    • 1
  1. 1.Institute of NeurologyThe Academy Republica Populara RominaBucarest

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