Acta Neuropathologica

, Volume 65, Issue 2, pp 166–167 | Cite as

Hypotensive brain stem necrosis in a stillborn

  • S. R. Taylor
  • U. Roessmann
Short Original Communications

Summary

Hypotensive brain stem necrosis is reported in a stillborn. Additional postmortem findings included evidence of intrauterine distress, shock, and a pure blood culture of group B β-hemolytic streptococci. These findings suggest group B β-hemolytic streptococcal sepsis in utero, with a subsequent episode of transitory circulatory failure prior to intrauterine demise.

Key words

Hypotensive brain stem necrosis Cardiac arrest encephalopathy Intrauterine, group B β-hemolytic streptococci Still birth 

References

  1. 1.
    Brierly JB, Graham DI, Adams JH, Simpson JA (1971) Neocortical death after cardiac arrest. Lancet II:560–565Google Scholar
  2. 2.
    Christensen KK, Christensen P, Hagerstrand I, Linden V, Nordbring F, Svenningsen N (1982) The clinical significance of group B streptococci. J Perinat Med 10:113–146Google Scholar
  3. 3.
    Dambska MM, Dydyk L, Szretter T, Wozniewicz J, Myers RE (1976) Topography of lesions in newborn and infant brains following cardiac arrest and resuscitation. Biol Neonate 29:194–206Google Scholar
  4. 4.
    Fenichel GM (1983) Hypoxic-ischemic encephalopathy in the newborn. Arch Neurol 40:261–266Google Scholar
  5. 5.
    Gilles FH (1969) Hypotensive brain stem necrosis. Selective symmetrical necrosis of tegmental neuronal aggregates following cardiac arrest. Arch Pathol Lab Med 88:32–41Google Scholar
  6. 6.
    Griffiths AD, Laurence KM (1974) The effect of hypoxia and hypoglycemia on the brain of the newborn human infant. Dev Med Child Neurol 16:308–319Google Scholar
  7. 7.
    Grunnet ML, Curless RG, Bray PF, Jung AL (1974) Brain changes in newborns from an intensive care unit. Dev Med Child Neurol 16:320–328Google Scholar
  8. 8.
    Janzer RC, Friede RL (1980) Hypotensive brain stem necrosis or cardiac arrest encephalopathy? Acta Neuropathol (Berl) 50:53–56Google Scholar
  9. 9.
    Leech RW, Alvord EC (1977) Anoxic-ischemic encephalopathy in the human neonatal period. The significance of brain stem involvement. ArchNeurol 34:109–113Google Scholar
  10. 10.
    Norman MG (1972) Antenatal neuronal loss and gliosis of the reticular formation, thalamus, and hypothalamus. A report of three cases. Neurology (NY) 22:910–916Google Scholar
  11. 11.
    Schneider H, Ballowitz L, Schachinger H, Hanefeld F, Drozus JU (1975) Anoxic encephalopathy with predominant involvment of basal ganglia, brain stem and spinal cord in the perinatal, period. Acta Neuropathol (Berl) 32:287–298Google Scholar

Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • S. R. Taylor
    • 1
  • U. Roessmann
    • 2
  1. 1.Dept. of PathologyUniversity Hospitals of Cleveland and Case Western Reserve UniversityClevelandUSA
  2. 2.Division of Neuropathology, Institute of PathologyUniversity Hospitals of Cleveland and Case Western Reserve UniversityClevelandUSA

Personalised recommendations