Acta Neuropathologica

, Volume 21, Issue 3, pp 194–203 | Cite as

Zur Morphologie transplacentar erzeugter neurogener Tumoren beim Goldhamster

  • H. D. Mennel
  • K. J. Zülch

Morphology of transplacentally induced neurogenic tumors in Syrian hamsters


Pregnant Syrian hamsters were given 30 mg/kg ethylnitrosurea on the 15th day of pregnancy. Among 29 newborn animals, 22 could be grown up, 14 of which developed malignant tumors. Besides tumors of the trigeminal nerve which appeared first, particularly tumors of peripheral nerves were observed. In addition one nephroblastoma and one melanoma of the subcutis were induced. There were no tumors of the brain and spinal cord. The peripheral nervous tumors showed intensive regressive changes. In general, these tumors can be classified within the group of “malignant neurinomas”.

Key words

Neurogenic Tumors Transplacentar Induction Ethylnitrosurea Malignant Neurinomas 


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Copyright information

© Springer-Verlag 1972

Authors and Affiliations

  • H. D. Mennel
    • 1
  • K. J. Zülch
    • 1
  1. 1.Abteilung für Allgemeine NeurologieMax-Planck-Institut für HirnforschungKöln-MerheimDeutschland

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