Acta Neuropathologica

, Volume 63, Issue 1, pp 80–82 | Cite as

Central nervous system of a thoracopagus

  • T. Wongmongkolrit
  • M. Lederhandler
  • U. Roessmann
Short Original Communications


Postmortem examination of the central nervous system (CNS) of a dicephalus thoracopagus tetrapus revealed two separate brains and spinal cords. On the conjoined side the spinal cord showed hypoplasia of the anterior horns and dorsal funiculi at the lower cervical and upper thoracic levels. Hypoplasia of the peripheral nerves, anterior horn cells, and dorsal funiculi is a consequence of a reduction in tissue mass due to a loss of inductive influence.

Key words

Nervous system Conjoined twins Thoracopagus 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Hori A, Fischer G, Dietrich-Schott B, Ikeda K (1982) Dimyelia, diplomyelia, and diastematomyelia. Clin Neuropathol 1:23–30Google Scholar
  2. 2.
    Jacobson M (1978) Developmental neurobiology, 2 edn Plenum Press, New York, pp 280, 287–292, 302–307Google Scholar
  3. 3.
    Moore KL (1973) The developing human. Clinical oriented embryology. Saunders, Philadelphia, pp 12–53, 306–334Google Scholar
  4. 4.
    Pearson J, Pytel BA (1981) Neuronal survival and peripheral tissue size during human embryogenesis: Study of a partial twinning. Dev Neurosci 4:142–149Google Scholar
  5. 5.
    Potter EL (1961) Pathology of the fetus and the infant, 2 edn. Year Book Medical Publishers, Chicago, pp 216–233Google Scholar
  6. 6.
    Slager UT, Anderson VM, Handmaker SD (1981) Cephalothoracopagus janiceps malformation. A contribution to the pathogenesis of cerebral malformation. Arch Neurol 38:103–108Google Scholar
  7. 7.
    Willis RA (1958) The borderland of embryology and pathology. Butterworth, London, pp 1–16, 17–53Google Scholar
  8. 8.
    Zimmermann AA (1967) Embryologic and anatomic considerations of conjoined twins. Birth Defects 3:18–27Google Scholar

Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • T. Wongmongkolrit
    • 1
  • M. Lederhandler
    • 2
  • U. Roessmann
    • 1
  1. 1.Division of Neuropathology, Institute of PathologyCase Western Reserve University and University Hospitals of ClevelandClevelandUSA
  2. 2.Dept. of Pathology, Institute of PathologyCase Western Reserve University and University Hospitals of ClevelandClevelandUSA

Personalised recommendations