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Dialysis myopathy

Report of 13 cases

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Thirteen patients hemodialyzed for chronic renal insufficiency developed progressive paresis of the proximal musculature. Biopsies of the deltoid muscles of ten patients showed selective atrophy of type 2 fibers, the cause of which seems to be related to the osteomalacia present in those patients. Purification of the water for dialysis prior to the procedure prevents the muscle alteration: however, once the lesion is established only renal transplant will permit recovery of the muscle strength of the patient.

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Bautista, J., Gil-Necija, E., Castilla, J. et al. Dialysis myopathy. Acta Neuropathol 61, 71–75 (1983).

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