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Acta Neuropathologica

, Volume 73, Issue 4, pp 409–410 | Cite as

Focal ependymal differentiation in the choroid plexus of human newborn brain confirmed by immunohistochemistry with monoclonal antibodies

  • M. Kasper
  • U. Karsten
Case Reports

Summary

Ependymal proliferation [“Ependymzotten”, G. Becker, Beitr Pathol Anat Allg Pathol 103:457–477 (1939)], found in choroid plexus of newborns, can be made easily visible by immunostaining with antiglial fibrillary acidic protein (GFAP) antibodies. The expression of both GFAP and cytokeratin is an unusual feature of these structures.

Key words

“Ependymzotte” Glial fibrillary acidic protein Choroid plexus epithelium Immunoperoxidase Cytokeratin 

References

  1. 1.
    Becker G (1939) Beiträge zur Orthologie und Pathologie der Plexus chorioidei und des Ependyms. Beitr Pathol Anat Allg Pathol 103:457–477Google Scholar
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    Kasper M, Goertchen R, Stosiek P, Perry G, Karsten U (1986) Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus. An Immunohistochemical study of intermediate filaments in neuro epithelial tissues. Virchows Arch [A] 410:173–177Google Scholar
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    Kasper M, Stosiek P, Typlt H, Karsten U (1987) Histological evaluation of three new monoclonal anticytokeratin antibodies. I. Normal tissues. Eur J Cancer Clin Oncol (in press)Google Scholar
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    Leonhardt H (1980) Ependym und circumventriculäre Organe. In: Oksche A, Vollrath L (eds) Handbuch der mikroskopischen Anatomie des Menschen, vol IV/10. Springer, Berlin Heidelberg New York, pp 177–666Google Scholar
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    Rubinstein LJ, Brucher J-M (1981) Focal ependymal differentiation in choroid plexus papillomas. An immunoperoxidase study. Acta Neuropathol (Berl) 53:29–33Google Scholar
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    Taratuto AL, Molina H, Monges J (1983) Choroid plexus tumors in infancy and childhood. Focal ependymal differentiation. Acta Neuropathol (Berl) 59:304–308Google Scholar

Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • M. Kasper
    • 1
  • U. Karsten
    • 2
  1. 1.Institute of PathologyDistrict HospitalGörlitzGermany
  2. 2.Department of Immunology, Institute of Molecular BiologyAcademy of Sciences of the Demoratic Republic of GermanyBerlin-BuchGermany

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