Advertisement

Acta Neuropathologica

, Volume 27, Issue 2, pp 181–184 | Cite as

Therapie-bedingte Form einer reno-cerebralen Oxalose?

  • R. Schröder
  • W. Féaux de Lacroix
  • U. Franzen
  • P. J. Klein
  • W. Müller
Article

Therapeutically induced form of reno-cerebral oxalosis?

Summary

Within a short period of time, we observed 6 cases with the appearance of calcium oxalate crystals in the renal tubuli and in the walls of cerebral arterioles. Reviewing the case histories showed that all of these patients had received large doses of xylitol and had shown subsequently disorders of consciousness. A possible deposition of oxalate crystals following high-dose-therapy with xylitol is discussed.

Key words

Calcium Oxalate Crystals Toxic Changes of Brain Vessels Toxic Meningoencephalitis Oxalate Metabolism Xylitol 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Bednář, B., Jirásek, A., Stejskal, J., Chytil, M.: Die sekundäre urämische Oxalose. Zbl. allg. Path. path. Anat.102, 289–297 (1961)Google Scholar
  2. Evans, G. W., Phillip, G., Mukherjee, T. M., Snow, M. R., Lawrence, J. R.: Identification of crystals deposited in brain and kidney after xylitol administration by biochemical, histochemical, and electron diffraction methods. J. clin. Path.26, 32–36 (1973)Google Scholar
  3. Hockaday, T. D. R., Clayton, J. E., Frederick E. W., Smith, L. H.: Primary hyperoxaluria. Medicine (Baltimore)43, 315–345 (1964)Google Scholar
  4. Hughes, D. T. D.: The clinical and pathological background of two cases of oxalosis. J. clin. Path.12, 498–509 (1959)Google Scholar
  5. Pons, C. A., Custer, R. P.: Acute ethylene glycol poisoning. A clinico-pathologic report of eighteen fatal cases. Amer. J. med. Sci.211, 544–552 (1946)Google Scholar
  6. Thomas, D. W., Edwards, J. B., Gilligan, J. E., Lawrence, J. R., Edwards, R. G.: Complications following intravenous administration of solutions containing xylitol. Med. J. Aust.1, 1238–1246 (1972)Google Scholar
  7. Wiebecke, B., Esser, A., Sieberth, H. G.: Die Oxalose. Med. Welt1970, 325–328Google Scholar

Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • R. Schröder
    • 1
    • 2
  • W. Féaux de Lacroix
    • 1
    • 2
  • U. Franzen
    • 1
    • 2
  • P. J. Klein
    • 1
    • 2
  • W. Müller
    • 1
    • 2
  1. 1.Neuropathologisches LaborPathologisches Institut der Universität KölnKöln 41Bundesrepublik Deutschland
  2. 2.Chirurgische Universitäts-Klinik KölnKölnDeutschland

Personalised recommendations