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Acta Neuropathologica

, Volume 69, Issue 1–2, pp 148–152 | Cite as

Melanotic neurofibroma: A case report with ultrastructural study

  • M. J. Payan
  • D. Gambarelli
  • P. Keller
  • A. Lachard
  • M. Garcin
  • C. Vigouroux
  • M. Toga
Original Works

Summary

The authors report a case of a solitary melanotic neurofibroma involving the temporomalar area in a 17-year-old man. Light-microscopic study reveals a benign neurofibroma including melanin deposits. Electron microscopy shows typical premelanosomes and melanosomes within Schwann cell cytoplasm. The literature is reviewed, and theories of histogenesis for this unusual tumor are discussed.

Key words

Nerve sheath tumors Melanotic neurofibroma Melanosomes 

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Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • M. J. Payan
    • 1
  • D. Gambarelli
    • 2
  • P. Keller
    • 3
  • A. Lachard
    • 2
  • M. Garcin
    • 3
  • C. Vigouroux
    • 4
  • M. Toga
    • 2
  1. 1.Laboratoire d'Anatomie PathologiqueHôpital Ste. MargueriteMarseilleFrance
  2. 2.Laboratoire de NeuropathologieFaculté de MédecineMarseille Cédex 5France
  3. 3.Service d'ORL et de Chirurgie cervico-facialeHôpital Ste. MargucriteMarseilleFrance
  4. 4.Service de RéanimationHôpital NordMarseilleFrance

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