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Intravesical instillation of Adriamycin for bladder tumors

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Summary

In the present series of trials, Adriamycin (ADM) intravesical instillation therapy was found to be effective against tumors of papillary morphology measuring <10 mm in diameter that were of low pathological stage and low histological grade. The rate of complete disappearance increased in proportion to the concentration of ADM and the duration of retention of the drug, although the efficacy rates were almost the same in each trial. On the other hand, side effects on the bladder were reduced when the instilled solution was lower in concentration and the retention time was short.

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References

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Authors and Affiliations

  1. Department of Urology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo-ku, 602, Kyoto, Japan

    Hiroshi Ohe, Hiroki Watanabe, Munekado Kojima & Shuichi Nakagawa

  2. Mishina Urological Office, Japan

    Teruo Mishina

Authors
  1. Hiroshi Ohe
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  2. Hiroki Watanabe
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  3. Teruo Mishina
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  4. Munekado Kojima
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  5. Shuichi Nakagawa
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Ohe, H., Watanabe, H., Mishina, T. et al. Intravesical instillation of Adriamycin for bladder tumors. Cancer Chemother. Pharmacol. 30 (Suppl 1), S45–S49 (1992). https://doi.org/10.1007/BF00686941

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  • DOI: https://doi.org/10.1007/BF00686941

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