Acta Neuropathologica

, Volume 37, Issue 1, pp 21–26 | Cite as

Primary actinomycoma of the third ventricle—The colloid cyst

A histochemical and ultrastructural study
  • James M. Powers
  • Helen M. Dodds
Original Investigations

Summary

Primary actinomycoma of the third ventricle has been reported to be a very rare form of central nervous system actinomycosis. Others have demonstrated actinomycotic-like colonies in colloid cysts of the third ventricle. We have confirmed these structures (HLS) in five colloid cysts and have demonstrated by various histochemical stains that they consist of desoxyribose nucleic acid, basic protein and phospholipid. Ultrastructurally, they consist of amorphous to granular electron dense material, probably deposited on a lamellar substructure. On the basis of the available information, we believe that the lesions, previously reported as primary actinomycomas, are actually colloid cysts containing degenerative HLS. The possible origin of the hyphal-like structures is discussed.

Key words

Fungus Actinomycosis Colloid cyst Degeneration 

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References

  1. Bollinger, V. O.: Über primäre Actinomykose des Gehirns beim Menschen. Münch. med. Wschr.34, 789–792 (1887)Google Scholar
  2. Bolton, C. F., Ashenhurst, E. M.: Actinomycosis of the brain. Canad. med. Ass. J.90, 922–928 (1964)Google Scholar
  3. Clark, G., Powers, J. M.: A consistent phosphotungstic acid hematoxylin stain for glial fibers. Stain Technol.51, 227–229 (1976)Google Scholar
  4. Dandy, W. E.: Benign tumors in the third ventricle of the brain, pp. 1–37. Springfield, Ill.: Ch. C. Thomas 1933Google Scholar
  5. Dublin, W. B.: Fundamentals of neuropathology, p. 116. Springfield, Ill.: Ch. C. Thomas 1967Google Scholar
  6. Fetter, B. F., Klintworth, G. K., Hendry, W. S.: Mycoses of the central nervous system, pp. 18–21. Baltimore, Maryland: Williams and Wilkins 1967Google Scholar
  7. Garvin, A. J., Spicer, S. S., Paremly, R. T., Munster, A. M.: Immunohistochemical demonstration of IgG in Reed-Sternberg and other cells in Hodgkin's disease. J. exp. Med.139, 1077–1083 (1974)Google Scholar
  8. Hallervorden, J.: Ein Aktinomykom im 3. Ventrikel. Arch. Psychiat. Nervenkr.95, 527–536 (1931)Google Scholar
  9. Landolt-Weber, U. M.: Ultrastruktur einer Kolloidcyste des dritten Ventrikels. Acta neuropath. (Berl.)26, 59–70 (1973)Google Scholar
  10. Mosberg, W. H., Jr., Blackwood W.: Mucus-secreting cells in colloid cysts of the third ventricle. J. Neuropath. exp. Neurol.13, 417–426 (1954)Google Scholar
  11. Orr, T. G.: Actinomycoma of the third ventricle, probably primary. J. Amer. med. Ass.127, 757 (1945)Google Scholar
  12. Puchtler, H., Sweat, F.: A combined hemoglobin-hemosiderin stain. Arch. Path.75, 588–590 (1963)Google Scholar
  13. Roque, A. L.: Chromotrope aniline blue method of staining Mallory bodies of Laennec's cirrhosis. Lab. Invest.2, 15–21 (1953)Google Scholar
  14. Russell D. S., Rubinstein, L. J.: Pathology of tumors of the nervous system, pp. 120–122; 166–168, Baltimore, Maryland: Williams and Wilkins 1971Google Scholar
  15. Schwartz, J., Hansen, J. L.: Paraphysial cyst of the third ventricle. Arch. Path.52, 280–287 (1951)Google Scholar
  16. Sternberg, C.: Zur Kenntnis der Aktinomykose des Gehirns. Z. Hyg. Infektkr.113, 151–159 (1931)Google Scholar
  17. Stevens, H.: Actinomycosis of the nervous system. Neurology (Minneap.)3, 761–772 (1953)Google Scholar

Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • James M. Powers
    • 1
  • Helen M. Dodds
    • 1
  1. 1.Department of Pathology, Medical University of South CarolinaVeterans Administration HospitalCharlestonUSA

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