, 83:331 | Cite as

Ultrastructural localization of cholecystokinin in endocrine cells of the dog duodenum by the immunogold technique

  • L. Usellini
  • C. Capella
  • A. Malesci
  • G. Rindi
  • E. Solcia


Cholecystokinin (CCK) has been localized by the immunogold technique in a type of endocrine cell of the dog duodenum characterized by small (166±38 nm) secretory granules with fairly dense, homogeneous core separated from its enveloping membrane by a thin clear space. The CCK cell is immunocytochemically distinct and cytologically different from other types of endocrine cells, as the secretin, GIP and motilin cells, already identified in the dog duodenum.


Secretin Secretory Granule Endocrine Cell Motilin Gastric Inhibitory Polypeptide 
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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • L. Usellini
    • 1
  • C. Capella
    • 1
  • A. Malesci
    • 2
  • G. Rindi
    • 3
  • E. Solcia
    • 3
  1. 1.Histopathology, Histochemistry and Ultrastructure Research CentreUniversity of Pavia at VareseItaly
  2. 2.Medical Clinic IIIUniversity of MilanoItalay
  3. 3.Department of Human PathologyUniversity of PaviaPaviaItaly

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