Calcified Tissue International

, Volume 52, Issue 1, pp 67–69 | Cite as

Lack of association between free testosterone and bone density separate from age in elderly males

  • Paul J. Drinka
  • Jack Olson
  • Steve Bauwens
  • Susan K. Voeks
  • Ian Carlson
  • Michael Wilson


It is unclear what proportion of the variance in bone density in elderly males is accounted for by testosterone status. We studied 112 ambulatory, elderly volunteers (mean age 71.7 years) and determined free testosterone (FT), as well as bone density measurements by photon absorptiometry at multiple sites. Our studies of 35 of these subjects 4 years later includedmorning FT and dual energy X-ray absorptiometry. There were no significant correlations between FT and bone density at multiple scanning sites with the effects of age partialed out. We suspect that our inability to detect a significant effect of FT on bone density was related to the relative strength of other determinants of bone density, as well as to the fact that FT values are far more dynamic than bone density.

Key words

Male Osteoporosis Free testosterone 


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Copyright information

© Springer-Verlag New York Inc. 1993

Authors and Affiliations

  • Paul J. Drinka
    • 1
    • 2
    • 3
  • Jack Olson
    • 1
    • 4
  • Steve Bauwens
    • 5
  • Susan K. Voeks
    • 3
  • Ian Carlson
    • 6
  • Michael Wilson
    • 2
  1. 1.Department of Internal Medicine and GeriatricsUniversity of WisconsinMadisonUSA
  2. 2.Veterans Administration Medical CenterMadisonUSA
  3. 3.Wisconsin Veterans HomeKingUSA
  4. 4.Mendota Mental Health InstituteMadisonUSA
  5. 5.Managed Care Resources, Inc.ChesapeakeUSA
  6. 6.Department of Pathology and Laboratory MedicineUniversity of Wisconsin HospitalMadisonUSA

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