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Nucleinsäure- und Elektrolytprofile im menschlichen Endometrium im Verlauf des mensuellen Cyclus

Nucleic acid and electrolyte contents in human endometrium during menstrual cycle

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Summary

An analysis of RNA-, DNA-, Magnesium and Calcium tissue contents was performed to have a base for functional studies of biochemical steroid hormone effects on nucleic acid metabolism in human endometrium. DNA and RNA showed a cyclic, parallel course with a first peak in the periovulatory phase and a second increase in the late secretory phase. In contrast to the Calcium tissue concentration, which showed a continuous decrease from the proliferative to the secretory phase, an increase of Magnesium concentration in the periovulatory phase was found.

Zusammenfassung

Als Basis für funktionelle Untersuchungen zu Wirkungen der Steroidhormone auf den Nucleinsäurestoffwechsel am menschlichen Endometrium, wurde eine biochemische Analyse des RNA- und DNA-Gehaltes sowie der Elektrolyte Calcium und Magnesium im Verlaufe des mensuellen Cyclus durchgeführt. Hierbei zeigten DNA und RNA ein cyclisches, parallel verlaufendes Verhalten mit einem ersten Konzentrationsmaximum um den Zeitpunkt der Ovulation und einen zweiten Anstieg in der späten Sekretion. Während die Calciumgewebskonzentration durch einen kontinuierlichen Abfall von der proliferativen zur sekretorischen Phase gekennzeichnet ist, zeigt Magnesium im periovulatorischen Bereich einen Konzentrationsanstieg.

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Authors and Affiliations

  1. Universitäts-Frauenklinik Bonn, Bonn

    R. Liedtke, I. Neukirchen & N. Lang

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  1. R. Liedtke
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  2. I. Neukirchen
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  3. N. Lang
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Liedtke, R., Neukirchen, I. & Lang, N. Nucleinsäure- und Elektrolytprofile im menschlichen Endometrium im Verlauf des mensuellen Cyclus. Arch. Gynak. 220, 35–42 (1975). https://doi.org/10.1007/BF00673146

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  • DOI: https://doi.org/10.1007/BF00673146

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