International Journal of Theoretical Physics

, Volume 30, Issue 2, pp 129–136 | Cite as

RNA self-splicing and energy localization

  • Ariel Fernández
Article
  • 30 Downloads

Abstract

We establish a mechanism for energy localization in regions of the sugar-phosphate RNA backbone which leads to the formation of transesterification or hydrolysis hot spots. In particular, our results account for the site specificity of the covalent cyclization and cycle reopening in the catalytic intervening sequence (IVS) of a ribosomal RNA.

Keywords

Hydrolysis Field Theory Elementary Particle Quantum Field Theory Transesterification 

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References

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Copyright information

© Plenum Publishing Corporation 1991

Authors and Affiliations

  • Ariel Fernández
    • 1
    • 2
  1. 1.Department of Biochemistry and Molecular BiologyMedical SchoolMiami
  2. 2.Department of ChemistryUniversity of MiamiCoral Gables

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