Archiv für Gynäkologie

, Volume 221, Issue 1, pp 5–9 | Cite as

Low molecular weight peptides with anti-thrombin and anti-urokinase activity isolated from human maternal and cord blood serum and amniotic fluid

  • Miecyslaw Uszyński
  • Fritz K. Beller


Peptides with antithrombin and anti-urokinase activity were isolated from maternal and cord blood serum and amniotic fluid from pregnant women at term. Chromatography data, fingerprinting and activity of peptide inhibitors revealed active peptides, which were similar to those recently isolated from human placenta. They are distinctly different from protein inhibitors previously isolated from human placenta.


Public Health Peptide Molecular Weight Pregnant Woman Cord Blood 
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Isolierung von Peptiden mit niedrigem Molekulargewicht mit Antithrombin und Antiurokinase aktiviert aus mütterlichem und Nabelschnurserum sowie Fruchtwasser


Peptide mit Antithrombin- und Urokinase-Hemmungsaktivität wurden aus mütterlichem Plasma, Nabelvenenblut und Fruchtwasser isoliert. Chromatographie, “Fingerprints” und die Aktivität von Peptidinhibitoren ergaben aktive Peptide, die ähnlich waren, wie sie von uns kürzlich aus der Plazenta isoliert worden waren. Sie unterscheiden sich wesentlich von Proteininhibitoren, die früher aus Plazenta gewonnen worden sind.


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Copyright information

© J. F. Bergmann-Verlag 1976

Authors and Affiliations

  • Miecyslaw Uszyński
    • 1
  • Fritz K. Beller
    • 1
  1. 1.Department of Obstetrics and GynecologyWestfälische Wilhelms UniversityMünsterFederal Republic of Germany

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