Chemistry of Heterocyclic Compounds

, Volume 23, Issue 2, pp 228–231 | Cite as

Reaction of 1,2,4-triazole-3-thiones with 1-chloro-2,3-epoxypropane

  • B. V. Trzhtsinskaya
  • é. I. Kositsyna
  • B. Z. Pertsikov
  • E. V. Rudakova
  • V. K. Voronov
  • G. G. Skvortsova
Article

Abstract

Addition of 1-chloro-2,3-epoxypropane to 1,2,4-triazole-3-thiones depending on the ratio of the reactants leads to the formation of 3-(1-chloro-2-hydroxypropyl)-3-(1-chloro-2-hydroxypropylthio)-1,2,4-triazoles. 3-Hydroxy-1,2,4-triazolo[2,3-b] tetrahydro-1,3-triazines have been synthesized by intramolecular cyclization of the monoadducts.

Keywords

Organic Chemistry Triazole Triazine Intramolecular Cyclization Epoxypropane 

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Copyright information

© Plenum Publishing Corporation 1987

Authors and Affiliations

  • B. V. Trzhtsinskaya
    • 1
  • é. I. Kositsyna
    • 1
  • B. Z. Pertsikov
    • 1
  • E. V. Rudakova
    • 1
  • V. K. Voronov
    • 1
  • G. G. Skvortsova
    • 1
  1. 1.Irkutsk Institute of Organic Chemistry, Siberian BranchAcademy of Sciences of the USSRIrkutsk

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