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Two new 17 α-hydroxyprogesterone transformation products fromNocardia DSM 43298

  • S. Choudhry
  • S. Halos
  • D. Krischenowski
  • G. Schmeda-Hirschmann
Research Papers

Abstract

Two new products: 9,10-seco-1,3,5(10)-pregnatrien-3,17 a-dihydroxy-9,20-dione and 9,10-seco-1,3,5(10)-pregnatrien-3,17a,20-triol-9-one, have been isolated as 17 α-hydroxyprogesterone transformation products fromNocardia DSM 43298. The structures were established by spectroscopic methods.

Key words

Biotransformation 17 α-hydroxyprogesterone Nocardia 

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References

  1. Kieslich, K. 1985 Microbial side-chain degradation of sterols.Journal of Basic Microbiology 25, 461–474.Google Scholar
  2. Mahato, S.B., Banerjee, S. & Podder, S. 1988 Oxidative side-chain and ring fission of pregnanes byArthrobacter simplex.Biochemistry Journal 255, 769–774.Google Scholar
  3. Owen, R.W., Mason, A.N. & Bilton, R.F. 1984 The anaerobic degradation of deoxycholic acid byPseudomonas sp. NCIB 10590.Tetrahedron 40, 421–426.Google Scholar
  4. Smith, L.L. 1984 Steroids. InBiotechnology, Vol. 6A, ed Kieslich, K., pp. 31–78. Weinberg: Verlag Chemie.Google Scholar

Copyright information

© Rapid Communications of Oxford Ltd 1993

Authors and Affiliations

  • S. Choudhry
    • 1
  • S. Halos
    • 2
  • D. Krischenowski
    • 3
  • G. Schmeda-Hirschmann
    • 4
  1. 1.Centre for Advanced Molecular BiologyUniversity of the PunjabLahorePakistan
  2. 2.Natural Sciences Research InstituteUniversity of the PhilippinesQuezon CityPhilippines
  3. 3.GBF, Mikrobielle StoffumwandlungBraunschweigGermany
  4. 4.Universidad de Talca, Departmento Ciencias BiológicasTalcaChile

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