Psychopharmacology

, Volume 88, Issue 2, pp 209–212 | Cite as

Effects of lithium and rubidium on shock-induced changes in open-field activity

  • Garth Hines
Original Investigations

Abstract

Lithium chloride and rubidium chloride were tested under conditions in which the effects of their chronic administration on aversively-controlled behavior could be assessed. Lithium attenuated shock-induced suppression of open-field activity when that suppression was under the control of mild or moderate stimulus parameters, but had no effect on the suppression produced by the presence of shock itself. Rubidium, on the other hand, increased shock-induced suppression under all conditions. When shock was removed and extinction of the activity suppression was investigated, lithium subjects failed to return to their original baseline activity levels, while subjects receiving rubidium recovered baselines in a manner indistinguishable from that observed in control animals.

Key words

Lithium Rubidium Shock-induced suppression Open-field activity CER Extinction 

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Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • Garth Hines
    • 1
  1. 1.Department of PsychologyUniversity of Arkansas at Little RockLittle RockUSA

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