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Journal of Solution Chemistry

, Volume 17, Issue 4, pp 383–397 | Cite as

Thermodynamic properties of peptide solutions 3. Partial molar volumes and partial molar heat capacities of some tripeptides in aqueous solution

  • Gavin R. Hedwig
Article

Abstract

Partial molar volumes, V 2 o , and partial molar heat capacities, C p,2 o , of the tripeptides glycylglycylglycine, glycylglycylalanine, glycylalanylglycine and alanylglycylglycine have been determined in aqueous solution at 25°C. For the three alanyl-containing tripeptides, the data indicate that the tripeptide-water interaction is influenced by the side chain position within the molecule. The results have been rationalized in terms of likely solutesolvent interactions. The V 2 o and C p.2 o data have also been used to calculate the contribution to these properties of a-CH3 side chain.

Key words

Partial molar heat capacity partial molar volume tripeptide aqueous solution density methyl group contribution 

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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • Gavin R. Hedwig
    • 1
  1. 1.Department of Chemistry and BiochemistryMassey UniversityPalmerston NorthNew Zealand

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