Annals of Hematology

, Volume 72, Issue 2, pp 93–95 | Cite as

Thromboembolism in a patient with transient eosinophilia

  • H. Yamamoto Mukai
  • H. Ninomiya
  • S. Mitsuhashi
  • Y. Hasegawa
  • T. Nagasawa
  • T. Abe
Case Report


We report here a case of thromboembolism occurring in a 29-year-old woman with transient eosinophilia. Eosinophilia for at least 11 days was followed by pulmonary embolism. Both reperfusion of pulmonary arteries and disappearance of deep vein thrombi were obtained by treatment with urokinase, tissue plasminogen activator, and heparin. Although the causes of eosinophilia were not specified, we suggested a causative correlation of elevated serum levels of eosinophil granule proteins with the development of thromboembolism.

Key words

Eosinophil Eosinophilia Major basic protein Thromboembolism Thrombomodulin 


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Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • H. Yamamoto Mukai
    • 1
  • H. Ninomiya
    • 1
  • S. Mitsuhashi
    • 1
  • Y. Hasegawa
    • 1
  • T. Nagasawa
    • 1
  • T. Abe
    • 1
  1. 1.Division of Hematology, Institute of Clinical MedicineUniversity of TsukubaTsukuba-shi, Ibaraki-ken 305Japan

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