European Journal of Clinical Pharmacology

, Volume 23, Issue 6, pp 475–477 | Cite as

Comparison of impedance cardiography and echocardiography for measurement of stroke volume

  • P. E. Aust
  • G. G. Belz
  • G. Belz
  • W. Koch


The relationship between stroke volume (SV) measured simultaneously by impedance cardiography (SV1) and echocardiography (SVE) has been analyzed. Change in stroke volume in 6 healthy volunteers was induced by passive head-up tilting (80°) and by oral administration of the sympathomimetic drug amezinium. A correlation ofr=0.83 (p j 0.01) was found between SVI and SVE calculated by the equation: SVE=16.0+(0.528×SVI). Though stroke volume is overestimated by impedance cardiography, the method may be useful for the clinical pharmacologist interested in a simple non-invasive tool to estimate stroke volume and change in it.

Key words

stroke volume measurement impedance cardiography amezinium echocardiography comparative measurement tilting 


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Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • P. E. Aust
    • 1
  • G. G. Belz
    • 1
  • G. Belz
    • 1
  • W. Koch
    • 2
  1. 1.Institute for Cardiovascular TherapyWiesbadenGermany
  2. 2.Department of Biostatistics, Pharmaceutical Research and DevelopmentBASFLudwigshafenGermany

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