Summary
This study evaluates the relationship between trait anxiety and both androgen and gonadotrophic hormone levels at rest and during severe physical exercise. Twelve volunteers were selected among 160 untrained male collegial students and classified as anxious (N=6) or non-anxious (N=6) subjects according to their scores on three trait-anxiety tests (STAI, IPAT, 16 PF). Serum Δ4-androgen (testosterone and Δ4-androstenedione), Δ4-androgen (DHEA and DHEA-SO4) and gonadotrophin (LH and FSH) concentrations were measured by radioimmunoassay before, during and after 20 minutes of intensive bicycle exercise (80% of maximal heart rate). Results indicate significantly lower serum Δ4-androgens in anxious subjects before exercise. However, for each subject and irrespective of his anxiety level, all measured serum androgen concentrations increased significantly during exercise, although Δ4-androstene-dione remained lower in anxious subjects than in non-anxious ones. Serum LH concentrations (but not FSH) were signicantly higher in anxious subjects throughout the observation periods. However, exercise induced in each subject a significant decrease in the serum level of both gonadotrophic hormones. The results suggest that trait anxiety level may constitute an important factor that affects both pre-exercise and exercise serum androgen concentrations in untrained subjects.
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References
Astrand PO, Rodahl K (1973) Manuel de Physiologie de l'exercice musculaire. Masson et Cie (ed) Paris
Brisson GR, Volle MA, Desharnais M, Dion M, Tanaka M (1977) Pituitary-gonadal axis in exercising man. Med Sci Sports 9:47
Brisson GR, DeCarufel D, Brault J, Volle MA, Audet A, Desharnais M, Lefrançois C (1981) Circulating Δ4-androgen levels and bicycle exercise in trained young men. In: Poortmans J, Niset G (eds) Biochemistry of exercise IV-B, International series on sports sciences, vol. II B. Baltimore University Park Press, pp 198–217
Brisson GR, Quirion A, Ledoux M, Rajote D, Pellerin-Massicotte J (1984) Influence of long-distance swimming on serum androgens in males. Horm Metab Res 16:160
Carstensen H, Terner N, Thorén L, Wide L (1972) Testosterone, luteinizing hormone and growth hormone in blood following surgical trauma. Acta Chir Scand 138:1–5
Cattell RB (1957) The IPAT anxiety scale, IPAT 1602 Coronado Drive, Champaign, IL
Cattell RB (1971) Manuel d'application du test 16 P.F. de R. B. Cattell: questionnaire de personnalité en 16 facteurs, 2ième édition, Les Editions du Centre de Psychologie Appliquée, Paris
Cumming DC, Brunsting LA, Strich G, Ries AL, Rebar RW (1986) Reproductive hormone increases in response to acute exercise in men. Med Sci Sports Exerc 18:369–373
Cumming DC, Brunsting LA, Strich G, Greenberg L, Ries AL, Rebar RW (1983a) Patterns of hormonal response to exercise in untrained men. Can J Appl Sport Sc 8:226
Cumming DC, Quigley ME, Yen SSC (1983b) Acute suppression of circulating testosterone levels by cortisol in men. J Clin Endocrinol Metab 57:671–673
Dessypris A, Kuoppasalmi K, Adlercreutz H (1976) Plasma cortisol, testosterone, androstenedione and luteinizing hormone (LH) in a non-competitive marathon run. J Steroid Biochem 7:33–37
Durnin JV, Womersley J (1974) Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 32:77–97
Free MJ (1977) Blood supply to the testis and its role in local exchange and transport of hormones. In: Johnson AD, Gomes WR (eds) The testis, vol. 4. Academic Press, New York, pp 39–90
Grossman A, Bouloux P, Price P, Drury PL, Lam KSL, Turner T, Thomas J, Besser GM, Sutton J (1984) The role of opioid peptides in the hormonal responses to acute exercise in man. Clin Sci 67:483–491
Karvonen MJ, Kentala E, Mustala O (1957) The effects of training on heart rate. Ann Med Exp Fenn 35:307–315
Kreuz LE, Rose RM, Jennings JR (1972) Suppression of plasma testosterone levels and psychological stress. Arch Gen Psych 26:479–482
Krulich L, Hefco E, Illner P, Read CB (1974) The effects of acute stress on the secretion of LH, FSH, prolactin and GH in the normal male rat, with comments on their statistical evaluation. Neuroendocrinology 16:293–311
Kuoppasalmi K, Näveri H, Rehunen S, Härkönen M, Adlercreutz H (1976) Effect of strenuous anaerobic running exercise on plasma growth hormone, cortisol, luteinizing hormone, testosterone, androstenedione, estrone and estradiol. J Steroid Biochem 7:823–829
Kuoppasalmi K, Näveri H, Härkönen M, Adlercreutz H (1980) Plasma cortisol, androstenedione, testosterone and luteinizing hormone in running exercise of different intensities. Scand J Clin Lab Invest 40:403–409
Kuusi T, Kostiainen E, Vartiainen E, Pitkänen L, Ehnholm C, Korhonen HJ, Nissinen A, Puska P (1984) Acute effects of marathon running on levels of serum lipoproteins and androgenic hormones in healthy males. Metabolism 33:527–531
Mason JW, Hartley LH, Kotchen TA, Mougey EH, Ricketts PT, Jones LG (1973) Plasma cortisol and norepinephrine responses in anticipation of muscular exercise. Psych Med 35:406–414
Rose RM, Bourne PG, Poe RO, Mougey EH, Collins DR, Mason JW (1969) Androgen responses to stress. II. Excretion of testosterone, epitestosterone, androsterone and etiocholanolone during basic combat training and under threat of attack. Psych Med 31:418–436
Saez JM, Morera AM, Haour F, Evain D (1977) Effects of in vivo administration of dexamethasone, corticotropin and human chorionic gonadotropin on steroidogenesis and protein and DNA synthesis of testicular interstitial cells in pre-pubertal rats. Endocrinology 101:1256–1263
Schmid P, Push HH, Wolf W, Pilger E, Pessenhofer H, Schwaberger G, Pristautz H, Pürstner P (1982) Serum FSH, LH, and testosterone in humans after physical exercise. Int J Sports Med 3:84–89
Sherins RJ, Patterson AP, Brightwell D, Udelsman R, Sartor J (1982) Alteration in the plasma testosterone: estradiol ratio: an alternative to the inhibin hypothesis. Ann NY Acad Sci 383:295–306
Spielberger CD, Gorsuch RL, Lushene RE (1970) Manual for the State-Trait-Anxiety Inventory. Consulting Psychologist Press, Palo Alto, California
Sutton JR, Coleman MJ, Casey J, Lazarus L (1973) Androgen responses during physical exercise. Br Med J 1:520–522
Sutton JR, Coleman MJ, Casey JH (1978) Testosterone production rate during exercise. In: Landry F, Orban WAR (eds) Proceeding of third symposium on biochemistry of exercise, vol. 3. Symposia Specialist, Miami, pp 227–234
Vogel RB, Books CA, Ketchum C, Zauner CW, Murray FT (1985) Increase of free and total testosterone during submaximal exercise in normal males. Med Sci Sports Exerc 17:119–123
Wilkerson JE, Horvath SM, Gutin B (1980) Plasma testosterone during treadmill exercise. J Appl Physiol: Respirat Environ Exercise Physiol 49:249–253
Young RJ, Ismail AH, Bradley A, Corrigan DL (1976) Effect of prolonged exercise on serum testosterone levels in adult men. Br J Sport Med 10:230–235
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Diamond, P., Brisson, G.R., Candas, B. et al. Trait anxiety, submaximal physical exercise and blood androgens. Europ. J. Appl. Physiol. 58, 699–704 (1989). https://doi.org/10.1007/BF00637379
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DOI: https://doi.org/10.1007/BF00637379