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European Journal of Clinical Pharmacology

, Volume 18, Issue 5, pp 429–432 | Cite as

Glucaric acid excretion. Analysis of the enzymatic assay and findings in smokers and non-smokers

  • K. Fiedler
  • E. Schröter
  • H. Cramer
Originals

Summary

Glucaric acid (GA) excretion in urine from cigarette smokers and non-smoking control subjects was determined enzymatically. There was no difference between GA 41.0±3.2 µmol/g creatinine (Cn; mean ± SEM) in smokers and GA 43.1±3.4 µmol/g Cn in the controls. Gas chromatographic analysis of the GA-glucarolactone equilibrium was carried out in an attempt to elucidate the striking discrepancies in previous results.

Key words

glucaric acid excretion smokers control subjects glucaric acid assay glucarolactone enzyme induction 

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Copyright information

© Springer-Verlag 1980

Authors and Affiliations

  • K. Fiedler
    • 1
    • 2
  • E. Schröter
    • 1
    • 2
  • H. Cramer
    • 1
    • 2
  1. 1.Abteilung Klinische NeurologieKlinikum der Albert-Ludwigs-UniversitätGermany
  2. 2.Neurophysiologie, Freiburg im BreisgauGermany

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