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Effect of acute sodium bicarbonate ingestion on excess C02 output during incremental exercise

  • Kohji Hirakoba
  • Atsuo Maruyama
  • Kouji Misaka
Article

Summary

The effect of bicarbonate ingestion on total excess volume of CO2 Output (CO2 excess), due to bicaronate buffering of lactic acid in exercise, was studied in eight healthy male volunteers during incremental exercise on a cycle ergometer performed after ingestion (0.3 g · kg−1 body mass) of CaCO3 (control) and NaHCO3 (alkalosis). The resting arterialized venous blood pH (P<0.05) and bicarbonate concentration ([HCO3]b;P<0.01) were significantly higher in acute metabolic alkalosis [AMA; pH, 7.44 (SD 0.03); [HCO3]b; 29.4 (SD 1.5) mmol·1-1] than in the control [pH, 7.39 (SD 0.03); [HCO3]b, 25.5 (SD 1.0) mmol·1−1]. The blood lactate concentrations ([la]b) during exercise below the anaerobic threshold (AT) were not affected by AMA, while significantly higher [la]b at exhaustion [12.29 (SD 1.87) vs 9.57 (SD 2.14) mmol·1−1,P < 0.05] and at 3 min after exercise [14.41 (SD 1.75) vs 12.26 (SD 1.40) mmol · l−1,P < 0.05] were found in AMA compared with the control. The CO2 excess increased significantly from the control [3177 (SD 506) ml] to AMA [3897 (SD 381) ml;P < 0.05]. The CO2 excess per body mass was found to be significantly correlated with both the increase of [la]b from rest to 3 min after exercise (Δ [la]b;r=0.926,P < 0.001) and with the decrease of [HCO3]b from rest to 3 min after exercise (Δ [HCO3]b;r=0.872,P<0.001), indicating that CO2 excess per body mass increased linearly with both Δ [lab and Δ [HCO3]b. As a consequence, CO2 excess per body mass per unit increase of [la]b (CO2 excess·mass−1·Δ [la]b) was similar for the two conditions. The present results would suggest that the relationship between CO2 excess and blood lactate accumulation was unaffected by acute metabolic alkalosis, because the relative contribution of bicarbonate buffering of lactic acid was the same as in the control.

Key words

CO2 excess Acute metabolic alkalosis Bicarbonate Blood pH Blood lactate accumulation 

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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Kohji Hirakoba
    • 1
  • Atsuo Maruyama
    • 2
  • Kouji Misaka
    • 2
  1. 1.Department of Health and Physical EducationKagoshima Keizai UniversityKagoshima-shiJapan
  2. 2.Laboratory of Exercise Physiology, Faculty of EducationKagoshima UniversityKagoshima-shiJapan

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