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Effects of 2-propyl 2-pentenoic acid on the acquisition of conditioned behavior with negative reinforcement in mice

  • Animal Studies
  • Original Investigations
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Abstract

2-Propyl 2-pentenoic acid (PPΔ), at a dose of 6 mg/kg (0.04 mM/kg), has a facilitating action on the acquisition of conditioned avoidance reactions. This effect of PPΔ is correlated with increase of the level of brain gamma-aminobutyric acid, following administration of PPΔ.

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Authors and Affiliations

  1. Laboratoire de Psychophysiologie, Université Louis Pasteur, 7, Rue de l'Université, F-67000, Strasbourg, France

    R. Misslin, A. Hinschberger, M. Maitre & L. Ciesielski

  2. Centre de Neurochimie, Centre National de la Recherche Scientifique, 7, Rue de l'Université, F-67000, Strasbourg, France

    R. Misslin, A. Hinschberger, M. Maitre & L. Ciesielski

Authors
  1. R. Misslin
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  2. A. Hinschberger
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  3. M. Maitre
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  4. L. Ciesielski
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Misslin, R., Hinschberger, A., Maitre, M. et al. Effects of 2-propyl 2-pentenoic acid on the acquisition of conditioned behavior with negative reinforcement in mice. Psychopharmacology 50, 53–54 (1976). https://doi.org/10.1007/BF00634154

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  • DOI: https://doi.org/10.1007/BF00634154

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