Chemistry of Heterocyclic Compounds

, Volume 24, Issue 11, pp 1256–1258 | Cite as

Synthesis of substituted 2-aminoquinoline-3-carboxylic acid amides

  • S. V. Ukhov
  • M. E. Konshin
Article
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Abstract

Substituted 3-(2-nitrophenyl)-2-cyanoacrylic acid amides were synthesized by the Knoevenagel reaction and were then reduced with iron in acetic acid to the corresponding 2-aminoquinoline-3-carboxylic acid amides.

Keywords

Iron Acetic Acetic Acid Organic Chemistry Amide 

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Literature Cited

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    T. H. Althius, L. J. Czuba, J. E. Hess Hans, and S. B. Kadin, U. S. Patent No. 3974161; Ref. Zh. Khim.,11, 0174P (1977).Google Scholar
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    M. Ishaq and J. Nath Ray, J. Chem. Soc., 2739 (1930).Google Scholar
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    K. Bauer, Berichte,71, 2226 (1938).Google Scholar

Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • S. V. Ukhov
    • 1
  • M. E. Konshin
    • 1
  1. 1.Perm State Pharmaceutical InstitutePerm

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