Chemistry of Heterocyclic Compounds

, Volume 24, Issue 11, pp 1229–1233 | Cite as

Synthesis, stereochemistry, and isomeric transformations of 4-aryl-5-aroyl-2-methylthio-2-imidazolines

  • V. A. Konovalov
  • O. N. Bubel'
  • I. G. Tishchenko
Article
  • 26 Downloads

Abstract

The corresponding 4-aryl-5-aroyl-2-methylthio-2-imidazolines were obtained by the reaction of complexes of cis- and trans-3-aroylaziridines and boron trifluoride with methyl thiocyanate. It is shown on the basis of spectral data that the aziridine ring is opened regiospecifically at the C(2) atom and stereospecifically with inversion of the configuration.

Keywords

Methyl Organic Chemistry Boron Spectral Data Thiocyanate 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature Cited

  1. 1.
    I. G. Tishchenko, O. N. Bubel', and V. A. Konovalov, Khim. Geterotsikl. Soedin., No. 7, 952 (1981).Google Scholar
  2. 2.
    A. McKenna, Canadian Patent No. 736484; Chem. Abstr.,65, 12212 (1966).Google Scholar
  3. 3.
    P. N. Gordon, German Patent No. 1272618; Chem. Abstr.,69, 95426 (1968).Google Scholar
  4. 4.
    S. Groszkowski, L. Korzycka, and I. Kresel, Acta Pol. Pharm.,42, 19 (1985).Google Scholar
  5. 5.
    M. Dubey, V. K. Verma, K. Shanker, J. N. Sinha, and K. Bhargava, Pharmazie,33, 268 (1978).Google Scholar
  6. 6.
    I. G. Tishchenko, O. N. Bubel', and V. A. Konovalov, Khim. Geterotsikl. Soedin., No. 1, 38 (1981).Google Scholar
  7. 7.
    A. M. Van Leusen, J. Wildeman, and O. H. Oldenziel, J. Org. Chem.,42, 1156 (1977).Google Scholar
  8. 8.
    I. G. Tishchenko, O. N. Bubel', and V. A. Konovalov, Khim. Geterotsikl. Soedin., No. 10, 1353 (1980).Google Scholar
  9. 9.
    I. G. Tishchenko, O. N. Bubel', V. A. Konovalov, and N. M. Fedoseeva, Vestnik Belorussk. Gosudarstv. Univ., No. 2, 27 (1979).Google Scholar

Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • V. A. Konovalov
    • 1
  • O. N. Bubel'
    • 1
  • I. G. Tishchenko
    • 1
  1. 1.A. N. Sevchenko Scientific-Research Institute of Applied Physical ProblemsMinsk

Personalised recommendations