Abstract
The reaction of N-tritylproline methyl ester with tert-butyl hypochlorite gave 2,4-dichloro-2-methoxycarbonyl-5-pyrroline, which is readily converted to 2-methoxycarbonyl-4-chloropyrrole. The intermediate products were identified by Chromatographic mass spectrometry when the reaction was carried out at low temperatures.
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A. V. Eremeev, F. D. Polyak, and é. é. Liepin'sh, Khim. Geterotsikl. Soedin., No. 5, 707 (1984).
A. Gordon and R. Ford, The Chemist's Guide [Russian translation], Mir, Moscow (1976), p. 306.
Z. Berustrin and D. Ben-Ishai, Tetrahedron,33, 881 (1977).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 894–896, July, 1988.
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Polyak, F.D., Eremeev, A.V., Gavars, M.P. et al. Chlorination of N-tritylproline methyl ester. Chem Heterocycl Compd 24, 733–735 (1988). https://doi.org/10.1007/BF00633164
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DOI: https://doi.org/10.1007/BF00633164