Journal of Neurology

, Volume 208, Issue 3, pp 191–199 | Cite as

Movement-associated cortical potentials with unilateral and bilateral simultaneous hand movement

  • H. Shibasaki
  • M. Kato


Cortical potentials associated with unilateral and bilateral simultaneous thumb opposition were studied in 9 healthy subjects. The P1 component, “pre-motion positivity”, was recognized in 5 out of 9 subjects on unilateral thumb movement. In all subjects in whom P1 was recognized, P1 was dominant over the cerebral hemisphere ipsilateral to the contracting muscles. On bilateral simultaneous thumb movement, however, P1 was not discerned in any subject. This is compatible with the assumption that P1 is related to an inhibition of imitative movement of the opposite hand (mirror movement). The N2 component had its onset after the start of muscle contraction in most cases, suggesting that N2 might not reflect activation of the corticospinal pathways.

Key words

Movement-associated potentials Pre-motion positivity Mirror movement 


Corticale Potentiale, assoziiert mit unilateralen und bilateralen gleichzeitigen Daumenoppositionen, wurden bei 9 gesunden Männern studiert. Die P1-Komponente, „prämotorische Positivierung“, wurde an der unilateralen Daumenbewegung bei 5 der 9 Versuchspersonen beobachtet. Bei allen Versuchspersonen, bei welchen P1 gesehen wurde, war P1 dominant über der homolateralen Hemisphäre. Bei bilateraler gleichzeitiger Daumenbewegung wurde P1 bei keiner Versuchsperson gefunden. Dieser Befund ist kompatibel mit der Annahme, daß P1 in Beziehung mit einer Hemmung der imitatorischen Bewegung der gegenseitigen Hand (mirror movement) steht. Die N2-Komponente begann in den meisten Fällen nach dem Beginn der Muskelkontraktion. Dieser Befund läßt vermuten, daß N2 nicht die Aktivierung der corticospinalen Bahnen reflektiert.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Becker, W., Hoehne, O., Iwase, K., Kornhuber, H. H.: Bereitschaftspotential, prämotorische Positivierung und andere Hirnpotentiale bei sakkadischen Augenbewegungen. Vis. Res.12, 421–436 (1972)Google Scholar
  2. Brodal, A.: Neurological anatomy, 2nd ed., 159 p. London: Oxford University Press 1969Google Scholar
  3. Deecke, L., Scheid, P., Kornhuber, H. H.: Distribution of readiness potential, pre-motion positivity, and motor potential of the human cerebral cortex preceding voluntary finger movements. Exp. Brain Res.7, 158–168 (1969)Google Scholar
  4. Donchin, E., Otto, D., Gerbrandt, L. K., Pribram, K. H.: While a monkey waits: Electrocortical events recorded during the foreperiod of a reaction time study. Electroenceph. clin. Neurophysiol.31, 115–127 (1971)Google Scholar
  5. Gerbrandt, L. K., Goff, W. R., Smith, D. B.: Distribution of the human average movement potential. Electroenceph. clin. Neurophysiol.34, 461–474 (1973)Google Scholar
  6. Gilden, L., Vaughan, H. G., Jr., Costa, L. D.: Summated human EEG potentials with voluntary movement. Electroenceph. clin. Neurophysiol.20, 433–438 (1966)Google Scholar
  7. Green, J. B.: An electromyographic study of mirror movements. Neurology (Minneap.)17, 91–94 (1967)Google Scholar
  8. Järvilehto, T., Fruhstorfer, H.: Differentiation between slow cortical potentials associated with motor and mental acts in man. Exp. Brain Res.11, 309–317 (1970)Google Scholar
  9. Karlin, L., Marty, M. J., Brauth, S. E., Mordkoff, A. M.: Auditory evoked potentials, motor potentials and reaction time. Electroenceph. clin. Neurophysiol.31, 129–136 (1971)Google Scholar
  10. Kornhuber, H. H., Deecke, L.: Hirnpotentialänderungen bei Willkürbewegungen und passiven Bewegungen des Menschen: Bereitschaftspotential und reafferente Potentiale. Pflügers Arch. ges. Physiol.284, 1–17 (1965)Google Scholar
  11. McAdam, D. W., Rubin, E. H.: Readiness potential, vertex positive wave, contingent negative variation and accuracy of perception. Electroenceph. clin. Neurophysiol.30, 511–517 (1971)Google Scholar
  12. Oikawa, T., Fujitani, Y., Uematsu, S.: Cerebral motor potentials accompanying voluntary and reactive movements. Electroenceph. clin. Neurophysiol.32, 204 (1972)Google Scholar
  13. Rosenfeld, J. P., Fox, S. S.: Movement-related macropotentials in cat cortex. Electroenceph. clin. Neurophysiol.32, 75–80 (1972)Google Scholar
  14. Vaughan, H. G., Jr., Costa, L. D., Gilden, L., Schimmel, H.: Identification of sensory and motor components of cerebral activity in simple reaction time tasks. Proc. 73rd Conv. Amer. Psychol. Assoc.1, 179–180 (1965)Google Scholar
  15. Vaughan, H. G., Jr., Costa, L. D., Ritter, W.: Topography of the human motor potential. Electroenceph. clin. Neurophysiol.25, 1–10 (1968)Google Scholar
  16. Vaughan, H. G., Jr., Gross, E. G., Bossom, J.: Cortical motor potential in monkeys before and after upper limb deafferentation. Exp. Neurol.26, 253–262 (1970)Google Scholar
  17. Walshe, F. M. R.: On the role of the pyramidal system in willed movements. Brain70, 329–354 (1947)Google Scholar
  18. Wilke, J. T., Lansing, R. W.: Variations in the motor potential with force exerted during voluntary arm movements in man. Electroenceph. clin. Neurophysiol.35, 259–265 (1973)Google Scholar

Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • H. Shibasaki
    • 1
  • M. Kato
    • 1
  1. 1.Department of Neurology, Neurological Institute, Faculty of MedicineKyushu UniversityFukuoka CityJapan

Personalised recommendations