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Structure of the new unusual diterpene alkaloid acofine from Aconitum karakolicum

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Abstract

The structure of the new diterpene alkaloid acofine, isolated from tubers ofAconitum karakolicum, has been shown by the x-ray structural method (diffractometer, CuKα, 1250 reflections, direct method, R=0.071). The IR, mass, and PMR spectrum of acofine and its monoacetate are considered. Acofine is the first chlorine-containing diterpene alkaloid, and also the first alkaloid of the napelline type with a 15,16β-acetonide group.

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Authors
  1. B. Tashkhodzhaev
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  2. M. N. Sultankhodzhaev
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  3. I. M. Yusupova
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Additional information

Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 267–272, March–April, 1993.

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Tashkhodzhaev, B., Sultankhodzhaev, M.N. & Yusupova, I.M. Structure of the new unusual diterpene alkaloid acofine from Aconitum karakolicum. Chem Nat Compd 29, 222–225 (1993). https://doi.org/10.1007/BF00630121

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  • DOI: https://doi.org/10.1007/BF00630121

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