Synthesis and acute toxicity of some phosphorylated derivatives of ephedrine alkaloids
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The results are given of the synthesis and a comparative study of the toxicities of some phosphorylated derivatives of the alkaloids l-ephedrine and d-pseudoephedrine. It has been shown that the introduction of phosphorus- and sulfur-containing fragments considerably lowers the toxicity of the alkaloids.
KeywordsAlkaloid Acute Toxicity Ephedrine Phosphorothioates Exophthalmos
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