Chemistry of Natural Compounds

, Volume 30, Issue 3, pp 371–372 | Cite as

Synthesis and acute toxicity of some phosphorylated derivatives of ephedrine alkaloids

  • S. D. Fazylov
  • A. M. Gazaliev
  • M. Zh. Zhurinov
  • R. Z. Kasenov
  • A. B. Tateeva
  • M. Z. Kokzhalova
Article
  • 32 Downloads

Abstract

The results are given of the synthesis and a comparative study of the toxicities of some phosphorylated derivatives of the alkaloids l-ephedrine and d-pseudoephedrine. It has been shown that the introduction of phosphorus- and sulfur-containing fragments considerably lowers the toxicity of the alkaloids.

Keywords

Alkaloid Acute Toxicity Ephedrine Phosphorothioates Exophthalmos 

References

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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • S. D. Fazylov
  • A. M. Gazaliev
  • M. Zh. Zhurinov
  • R. Z. Kasenov
  • A. B. Tateeva
  • M. Z. Kokzhalova

There are no affiliations available

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