Skip to main content
Log in

Possibilities and limitations of limb-preserving therapy for bone tumors today

  • Symposium of the Cooperative Osteosarcoma Study Group — COSS 80
  • A Combined Diagnostic and Therapeutic Approach to Osteosarcoma Treatment May 7, 1982 in Viena
  • Published:
Journal of Cancer Research and Clinical Oncology Aims and scope Submit manuscript

Summary

To sum up, modern resection and extremity-preserving therapy is characterized by the following aspects: (1) The surgical procedure must be appropriate for the stage of the tumor. (2) From a functional point of view, the results of the resection treatment have so far been encouraging. (3) In spite of considerable technical progress, the implantation of bone-replacement endoprostheses as a treatment for primary osteosarcoma of the extremities must sill be considered to be at the experimental stage.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Böhler J (1959) Marknagelarthrodese des Kniegelenkes mit Umkipp-Plastik. Chir Praxis 3:427

    Google Scholar 

  • Campanacci M (1975) Resection endoprosthesis of the proximal humerus. Chir Organi Mov 62:465

    Google Scholar 

  • Campanacci M, Costa P (1979) Total resection of distal femur or proximal tibia for bone tumors. J Bone Joint Surg (Br) 61:455

    Google Scholar 

  • Coley BL (1960) Neoplasms of bone and related conditions. 2nd edn. P. B. Hoeber, New York

    Google Scholar 

  • Coventry MB, Dahlin DC (1957) Osteogenic sarcoma: Critical analysis of 430 cases. J Bone Joint Surg (Am) 39:741

    Google Scholar 

  • Enneking WF, Shirley PD (1977) Resection-arthrodesis for malignant and potentially malignant lesions about the knee using an intramedullary rod and local bone grafts. J Bone Joint Surg (Am) 59:223

    Google Scholar 

  • Enneking WF, Dunham WK (1978) Resection and reconstruction for primary neoplasm involving the innominate bone. J Bone Joint Surg (Am) 60:731

    Google Scholar 

  • Enneking WF, Spanier SS, Goodman MA (1980) A system for the surgical staging of muskuloskeletal sarcoma. Clin Orthop 153:106

    Google Scholar 

  • Juvara E (1921) Procédé de résection de la partie supérieur du tibia. Presse Med 29:291

    Google Scholar 

  • Kolarz G, Salzer M, Salzer-Kuntschik M, Willvonseder R, Höfer R (1973) Die Bedeutung der Knochenszintigraphie für Diagnose und Therapie des Osteosarkoms der langen Röhrenknochen. Arch Orthop Unfallchir 76:333

    Google Scholar 

  • Kotz R (1978) Osteosarkom 1978. Die Wende der Prognose durch adäquate Chirurgie und adjuvante Chemotherapie. Wien Klin Wochenschr 90 (Suppl):93

    Google Scholar 

  • Kotz R, Leber H, Ramach W, Salzer M, Salzer-Kuntschik M, Sekera J, Urban C (1979) Chirurgische Maßnahmen beim Osteosarkom unter dem Aspekt einer wirksamen Chemotherapie. Therapiewoche 29:6658–6664

    Google Scholar 

  • Kotz R, Salzer M (1982) Rotation-plasty for childhood osteosarcoma of the distal part of the femur. J Bone Joint Surg (Am) 64:959–969

    Google Scholar 

  • Kotz R, Engel A (to be published) Cement-free design of a tumor prosthesis for osteosarcoma of the distal femur and proximal tibia with a new fixation technique for the ligamentum patellae. Thieme-Stratton New York

  • Lichtenstein L (1972) Bone tumors, 4th edn. Mosby, St. Louis

    Google Scholar 

  • Mankin HJ (to be published) Allograft replacement for the management skeletal defects incurred in tumor surgery or trauma. Thieme-Stratton, New York

  • Marcove RC, Mike CV, Hajek LV, Levin AG, Hutter RPV (1970) Osteogenic sarcoma under the age of twenty-one. J Bone Joint Surg (Am) 52:411

    Google Scholar 

  • Marcove RC, Lewis MM, Rosen G, Huvos AG (1976) Total femur and total knee replacement. Clin Orthop 126:147

    Google Scholar 

  • Marcove RC, Lewis MM, Huvos AG (1977) En bloc upper humeral interscapulo-thoracic resection. Clin Orthop 124:219

    Google Scholar 

  • Marcove RC, Rosen G (1980) En bloc resections for osteogenic sarcoma. Cancer 45:3040

    Google Scholar 

  • Merle d'Aubigne R, Dejouany JP (1958) Diaphyso-epiphysal resection for bone tumour at the knee. J Bone Joint Surg (Br) 40:385

    Google Scholar 

  • Rosen G, Marcove RC, Caparros B, Nirenberg A, Kosloff C, Huvos AG (1979) Primary oesteogenic sarcoma. The rationale for preoperative chemotherapy and delayed surgery. Cancer 43:2163–2177

    Google Scholar 

  • Salzer M, Salzer-Kuntschik M (1969) Vergleichende röntgenologisch-pathologisch-analogische Untersuchungen von Osteosarkomen in Hinblick auf die Amputationshöhe. Arch Orthop Unfallchir 65:322

    Google Scholar 

  • Salzer M, Salzer-Kuntschik M, Zhuber K, Price CHG, Willer HG, Immenkamp M, Matejovsky Z, Keyl W, Groh P (1976) Therapie und Prognose des kindlichen Osteosarkoms. Arch Orthop Unfallchir 85:279

    Google Scholar 

  • Salzer M, Knahr K, Salzer-Kuntschik M (1977) Indication for radical resection of malignant bone tumors. Results in forty-six cases. Ital J Orthop Traumatol III/2:155

    Google Scholar 

  • Salzer M, Knahr K, Locke H, Stärk N, Matejovsky Z, Plenk H Jr, Punzet G, Zweymüller K (1979) A bioceramic endoprosthesis for the replacement of the proximal humerus. Arch Orthop Traumatol Surg 93:169

    Google Scholar 

  • Salzer M, Knahr K, Kotz R, Kristen H (1981) Treatment of osteosarcomata of the distal femur by rotation-plasty. Arch Orthop Traumatol Surg 99:131–136

    Google Scholar 

  • Sim FH, Ivins JC, Pritchard DJ (1978) Surgical treatment of osteogenic sarcoma at the Mayo Clinic. Cancer Treat Rep 62:205

    Google Scholar 

  • Sim FH, Chao EYS (1979) Prosthetic replacement of the knee and a large segment of the femur or tibia. J Bone Joint Surg (Am) 61:887

    Google Scholar 

  • Winkler K, Beron G et al. (1983) Adjuvant chemotherapy in osteosarcoma effects of cisplatinum. BCD and fibroblast interferon in sequential combination with HD-MTX and adriamycin. Preliminary results of the COSS-80 study. J Cancer Res Clin Oncol 106(suppl):1–7

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kotz, R. Possibilities and limitations of limb-preserving therapy for bone tumors today. J Cancer Res Clin Oncol 106 (Suppl 1), 68–76 (1983). https://doi.org/10.1007/BF00625055

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00625055

Key words

Navigation