, Volume 6, Issue 3, pp 189–195 | Cite as

An analysis of some batch and continuous kinetic data of specific monoclonal antibodt production from hybridomas

  • P. J. Phillips
  • C. P. Marquis
  • J. P. Barford
  • C. Harbour
Original Research Paper


An analysis of batch and continuous kinetic data obtained from hybridoma cell cultures has been performed with particular reference to the existence of specific antibody production profiles. The results presented by several groups, including our own, have been studied. Our analysis suggests that different interpretations of the data can be made to those previously presented in the literature. In view of the significance of these profiles, particularly in terms of production strategies designed to maximise antibody production, we believe that more consideration needs to be given to accuracy in reporting of kinetic studies in the future.


Cell Culture Specific Antibody Kinetic Study Kinetic Data Antibody Production 
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Copyright information

© Kluwer Academic Publishers 1991

Authors and Affiliations

  • P. J. Phillips
    • 1
  • C. P. Marquis
    • 1
  • J. P. Barford
    • 1
  • C. Harbour
    • 2
  1. 1.Department of Chemical EngineeringUniversity of SydneyAustralia
  2. 2.Department of Infectious DiseasesUniversity of SydneyAustralia

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